Literature DB >> 12355406

Chondrosarcoma of bone: functional outcome and quality of life.

I C M Van Der Geest1, P Servaes, H W B Schreuder, G Bleijenberg, C A H H V M Verhagen, M Pruszczynski, J A M Lemmens, R P H Veth.   

Abstract

BACKGROUND AND OBJECTIVES: Outcome studies of chondrosarcoma have so far only reported oncological and functional results. Quality-of-life assessment becomes more important because more long-term survival after treatment of malignant diseases occur. The objective of this study is to analyze functional outcome and quality of life.
METHODS: Functional evaluation of the patients was carried out according to the MSTS functional scoring system. For assessment of quality of life, questionnaires were used.
RESULTS: Response of the questionnaires sent to 45 disease-free patients was 84%. The mean functional score of these 38 patients was 74% (20-100%). Best functional results were seen after bone graft reconstruction and curettage and cryosurgery with reconstruction. Quality-of-life analysis revealed a mean global health status of 75 (66-84). Furthermore, 24% of the patients experienced severe fatigue. Patients reported more problems with regard to physical functioning and sleep in comparison with healthy controls. No correlation was found between global health status scores and functional scores.
CONCLUSIONS: Functional scores depend on the type of treatment with best results after curettage and cryosurgery. Quality-of-life analysis reveals problems on several domains, including fatigue, physical functioning and sleep. Copyright 2002 Wiley-Liss, Inc.

Entities:  

Mesh:

Year:  2002        PMID: 12355406     DOI: 10.1002/jso.10144

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

Review 1.  The clinical management of chondrosarcoma.

Authors:  Richard F Riedel; Nicole Larrier; Leslie Dodd; David Kirsch; Salutario Martinez; Brian E Brigman
Journal:  Curr Treat Options Oncol       Date:  2009-02-24

2.  Physical Function and Quality of Life After Resection of Mobile Spine Chondrosarcoma.

Authors:  Nuno Rui Paulino Pereira; Stein J Janssen; Nicky Stoop; Stefan Hartveldt; Yen-Lin E Chen; Thomas F DeLaney; Francis J Hornicek; Joseph H Schwab
Journal:  Global Spine J       Date:  2019-02-18

3.  High fatigue scores before and after surgical treatment of bone and soft tissue tumors.

Authors:  Ingrid C M VAN DER Geest; Hans Knoop; René P H Veth; H W Bart Schreuder; Gijs Bleijenberg
Journal:  Exp Ther Med       Date:  2012-10-31       Impact factor: 2.447

Review 4.  Unravelling the heterogeneity of soft tissue and bone sarcoma patients' health-related quality of life: a systematic literature review with focus on tumour location.

Authors:  Dide den Hollander; Winette T A Van der Graaf; Marco Fiore; Bernd Kasper; Susanne Singer; Ingrid M E Desar; Olga Husson
Journal:  ESMO Open       Date:  2020-10
  4 in total

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