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Literature DB >> 12354347

Emerging role of botulinum toxin in the treatment of neurogenic and non-neurogenic voiding dysfunction.

Christopher P Smith¹, George T Somogyi, Michael B Chancellor.

Abstract

Botulinum toxin (BTX) is the most lethal naturally occurring toxin known to mankind. Why, then, would an urologist want to use this agent to poison the bladder or urethral sphincter? This article reviews the mechanisms underlying the effects of BTX treatment, summarizes the current usage of this agent within the urologic community, and provides perspectives on future targets of this therapy.

Entities: Chemical

Mesh：

Substances：

Year: 2002 PMID： 12354347 DOI： 10.1007/s11934-002-0081-9

Source DB: PubMed Journal: Curr Urol Rep ISSN： 1527-2737 Impact factor: 2.862

24 in total

Review 1. Pharmacology and immunology of botulinum toxin serotypes.

Authors: K R Aoki
Journal: J Neurol Date: 2001-04 Impact factor: 4.849

2. Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients.

Authors: D D Dykstra; A A Sidi; A B Scott; J M Pagel; G D Goldish
Journal: J Urol Date: 1988-05 Impact factor: 7.450

3. A method for the measurement of [3H]-glutamate release from cultured dorsal root ganglion neurons.

Authors: J R Purkiss; M J Welch; S Doward; K A Foster; C P Quinn
Journal: Biochem Soc Trans Date: 1998-05 Impact factor: 5.407

4. The effects of purified botulinum neurotoxin type A on cholinergic, adrenergic and non-adrenergic, atropine-resistant autonomic neuromuscular transmission.

Authors: I MacKenzie; G Burnstock; J O Dolly
Journal: Neuroscience Date: 1982-04 Impact factor: 3.590

5. Botulinum toxin A for spasticity, muscle spasms, and rigidity.

Authors: M A Grazko; K B Polo; B Jabbari
Journal: Neurology Date: 1995-04 Impact factor: 9.910

6. Botulinum A toxin for the treatment of spasmodic torticollis: dysphagia and regional toxin spread.

Authors: G E Borodic; M Joseph; L Fay; D Cozzolino; R J Ferrante
Journal: Head Neck Date: 1990 Sep-Oct Impact factor: 3.147

7. Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary results.

Authors: B Schurch; M Stöhrer; G Kramer; D M Schmid; G Gaul; D Hauri
Journal: J Urol Date: 2000-09 Impact factor: 7.450

8. Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals.

Authors: A de Paiva; F A Meunier; J Molgó; K R Aoki; J O Dolly
Journal: Proc Natl Acad Sci U S A Date: 1999-03-16 Impact factor: 11.205

9. Motor responses of the urinary bladder and skeletal muscle in botulinum intoxicated rats.

Authors: F G Carpenter
Journal: J Physiol Date: 1967-01 Impact factor: 5.182

10. Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds.

Authors: G Schiavo; A Santucci; B R Dasgupta; P P Mehta; J Jontes; F Benfenati; M C Wilson; C Montecucco
Journal: FEBS Lett Date: 1993-11-29 Impact factor: 4.124

4 in total

1. Intravesical electromotive administration of botulinum toxin type A in improving the bladder and bowel functions: Evidence for novel mechanism of action.

Authors: Abdol-Mohammad Kajbafzadeh; Hamed Ahmadi; Laleh Montaser-Kouhsari; Shabnam Sabetkish; Sanam Ladi-Seyedian; Masoud Sotoudeh
Journal: J Spinal Cord Med Date: 2019-04-18 Impact factor: 1.985