Literature DB >> 12353712

Fibroblastic rheumatism: a case without rheumatological symptoms.

Laura Colonna1, Claudio Barbieri, Giovanni Di Lella, Giovanna Zambruno, Giorgio Annessi, Pietro Puddu.   

Abstract

Fibroblastic rheumatism is a rare syndrome characterized by the association of multiple cutaneous nodules with symmetric polyarthritis. We report on a patient who presented a 4-year history of pink to skin-coloured nodular lesions symmetrically localized at para-articular sites without evident rheumatological symptoms. Histopathology of a skin nodule led to the diagnosis of fibroblastic rheumatism showing a poorly circumscribed dermal proliferation of spindle and stellate fibroblast-like cells embedded in thickened collagen bundles with a marked reduction of elastic fibres. X-rays of both hands and feet showed metacarpophalangeal, metatarsalphalangeal and interphalangeal erosions, unexpected by patient history. This case of fibroblastic rheumatism appears unique in view of the absence of any clinical manifestation of polyarthritis at 7 years from appearance of skin lesions.

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Year:  2002        PMID: 12353712     DOI: 10.1080/00015550260132505

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   4.437


  2 in total

1.  Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism.

Authors:  Juliane Aline Paupitz; Jozélio Freire de Carvalho
Journal:  Rheumatol Int       Date:  2010-03-26       Impact factor: 2.631

Review 2.  Fibroblastic rheumatism: an uncommon arthritis. A case-based review.

Authors:  A Pieta; A Zioga; A Skalkou; A I Venetsanopoulou; A A Drosos; P V Voulgari
Journal:  Rheumatol Int       Date:  2021-10-05       Impact factor: 2.631

  2 in total

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