Literature DB >> 12351538

Impact of patients' choice for single embryo transfer of a top quality embryo versus double embryo transfer in the first IVF/ICSI cycle.

D De Neubourg1, K Mangelschots, E Van Royen, M Vercruyssen, G Ryckaert, M Valkenburg, J Barudy-Vasquez, J Gerris.   

Abstract

BACKGROUND: The aim of this study was to evaluate the impact of transferring a single top quality embryo in the first IVF/ICSI cycle of patients <38 years old who chose to have one or two embryos transferred.
METHODS: A total of 262 patients participated in the study, and 243 transfers were performed: 156 (64%) patients chose the transfer of a single top quality embryo, if available, and two non-top quality embryos if not available; 87 (36%) patients chose to have a double embryo transfer regardless of embryo quality.
RESULTS: In the first group an ongoing pregnancy rate of 40% (63/156) with a twin pregnancy rate of 2% (1/63) was achieved. In the second group the ongoing pregnancy rate was 44% (38/87) with 26% (10/38) twin pregnancies. In the patient group with only one embryo transferred, irrespective of the patient's choice, the ongoing pregnancy rate was 43% (54/127) with no twin pregnancies. For the study population as a whole, the ongoing pregnancy rate was 42% (101/243) with 11% (11/101) twins.
CONCLUSION: We conclude that the introduction of single embryo transfer in the first IVF/ICSI cycle is highly acceptable in women <38 years old.

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Year:  2002        PMID: 12351538     DOI: 10.1093/humrep/17.10.2621

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  8 in total

1.  Selection of embryos for day-3 transfer at the pronuclear-stage and pronuclear-stage cryopreservation results in high delivery rates in fresh and frozen cycles.

Authors:  Diane G Hammitt; Christopher A Sattler; Misty L Manes; Anita P Singh
Journal:  J Assist Reprod Genet       Date:  2004-07       Impact factor: 3.412

2.  The impact of pronuclear orientation to select chromosomally normal embryos.

Authors:  Edson Júnior Borges; Lia Mara Rossi; Leila Farah; Patricia Guilherme; Claudia C Rocha; Valdemar Ortiz; Assumpto Júnior Iaconelli
Journal:  J Assist Reprod Genet       Date:  2005-03       Impact factor: 3.412

3.  Pregnancy outcome and live birth after IVF and ICSI according to embryo quality.

Authors:  Patricia Fauque; Roger Léandri; Françoise Merlet; Jean-Claude Juillard; Sylvie Epelboin; Juliette Guibert; Pierre Jouannet; Catherine Patrat
Journal:  J Assist Reprod Genet       Date:  2007-03-06       Impact factor: 3.412

4.  Vitrification of human blastocysts previously cryopreserved by slow controlled-rate freezing at the cleavage stage.

Authors:  S Lierman; E Van den Abbeel; P De Sutter
Journal:  J Assist Reprod Genet       Date:  2014-01-04       Impact factor: 3.412

5.  Defining women who are prone to have twins in in vitro fertilization--a necessary step towards single embryo transfer.

Authors:  Dan Hellberg; Maria Blennborn; Staffan Nilsson
Journal:  J Assist Reprod Genet       Date:  2005-05       Impact factor: 3.412

6.  The Association Between Embryo Quality, Number of Transferred Embryos and Live Birth Rate After Vitrified Cleavage-Stage Embryos and Blastocyst Transfer.

Authors:  Qianqian Zhu; Jiaying Lin; Haoyuan Gao; Ningling Wang; Bian Wang; Yun Wang
Journal:  Front Physiol       Date:  2020-08-14       Impact factor: 4.566

7.  Comparisons of benefits and risks of single embryo transfer versus double embryo transfer: a systematic review and meta-analysis.

Authors:  Shujuan Ma; Yangqin Peng; Liang Hu; Xiaojuan Wang; Yiquan Xiong; Yi Tang; Jing Tan; Fei Gong
Journal:  Reprod Biol Endocrinol       Date:  2022-01-27       Impact factor: 5.211

8.  Chromosome abnormalities and viability of vitrified eight-cell mouse embryos at presence of two different cryoprotectants at different storage durations.

Authors:  Shabnam Zarei Moradi; Anahita Mohseni Meybodi; Hamid Gourabi; Hossein Mozdarani; Zahra Mansouri
Journal:  Cell J       Date:  2013-02-20       Impact factor: 2.479

  8 in total

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