| Literature DB >> 12350162 |
Sei-Joon Jeong1, Ryuichi Higuchi, Tomofumi Miyamoto, Mayumi Ono, Michihiko Kuwano, Shunsuke F Mawatari.
Abstract
A new antiangiogenic compound, bryoanthrathiophene (1), together with two known compounds, 5,7-dihydroxy-1-methoxycarbonyl-6-oxo-6H-anthra[1,9-bc]thiophene (2) and 1,8-dihydroxyanthraquinone (3), was isolated from the bryozoan Watersipora subtorquata (d'Orbigny, 1852) using bioassay-guided fractionation methods. Among them, bryoanthrathiophene (1) exhibited the most potent antiangiogenic activity on BAEC (bovine aorta endothelial cell) proliferation.Entities:
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Year: 2002 PMID： 12350162 DOI： 10.1021/np010577+
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050