| Literature DB >> 12350157 |
Nicolai Zederkopff Ballin1, Maminata Traore, Halidou Tinto, Archibald Sittie, Per Mølgaard, Carl Erik Olsen, Arsalan Kharazmi, Søren Brøgger Christensen.
Abstract
Fractionation of an ethanol extract of roots of Cochlospermum tinctorium afforded five compounds: 3-O-E-p-coumaroylalphitolic acid (1), cochloxanthin (2), dihydrocochloxanthin (3), alphitolic acid (4), and 1-hydroxytetradecan-3-one (5). This is the first example of a 1-hydroxyalkan-3-one obtained from plant material after gentle workup. The antiplasmodial activities of the compounds were determined, and the IC(50) value of 3-O-E-p-coumaroylalphitolic acid was 2.3 microM.Entities:
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Year: 2002 PMID： 12350157 DOI： 10.1021/np020008h
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050