Literature DB >> 1233234

Urinary excretion of amantadine by the elderly.

C Montanari, P Ferrari, A Bavazzano.   

Abstract

The urinary excretion of single or multiple oral doses of amantadine hydrochloride by three elderly patients has been studied by gas chromatography. Steady state amounts in urine were about 230-240 mg per day. The half life of urinary excretion was approximately 34.17 hours. Urine collection from aged subjects is difficult.

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Year:  1975        PMID： 1233234     DOI： 10.1007/bf00562661

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  8 in total

1.  Amantadine in depression.

Authors:  S Vale; M A Espejel; J C Dominguez
Journal:  Lancet       Date:  1971-08-21       Impact factor: 79.321

2.  Effects of amantadine hydrochloride on catecholamine metabolism in the brain of the rat.

Authors:  R J Baldessarini; J F Lipinski; K V Chace
Journal:  Biochem Pharmacol       Date:  1972-01       Impact factor: 5.858

3.  Absorption, distribution and excretion of amantadine hydrochloride.

Authors:  W E Bleidner; J B Harmon; W E Hewes; T E Lynes; E C Hermann
Journal:  J Pharmacol Exp Ther       Date:  1965-12       Impact factor: 4.030

4.  Acute toxic psychosis from suicidal overdosage of amantadine.

Authors:  S Fahn; G Craddock; G Kumin
Journal:  Arch Neurol       Date:  1971-07

5.  Increased synthesis and release of dopamine in the striatum of the rat after amantadine treatment.

Authors:  B Scatton; A Cheramy; M J Besson; J Glowinski
Journal:  Eur J Pharmacol       Date:  1970       Impact factor: 4.432

6.  The antiparkinson properties of amantadine in drug-induced parkinsonism.

Authors:  J T Kelly; F S Abuzzahab
Journal:  J Clin Pharmacol New Drugs       Date:  1971 May-Jun

7.  Clinical trial with amantadine and pemoline in elderly patients.

Authors:  C Montanari; G F Vallecorsi; A Bavazzano; G D'Ayalavalva; P Sanesi
Journal:  Age Ageing       Date:  1976-02       Impact factor: 10.668

8.  A controlled study of the clinical effects of amantadine hydrochloride (Symmetrel).

Authors:  E M Merrick; P P Schmitt
Journal:  Curr Ther Res Clin Exp       Date:  1973-08
  8 in total
  3 in total

1.  Pyroelectricity Assisted Infrared-Laser Desorption Ionization (PAI-LDI) for Atmospheric Pressure Mass Spectrometry.

Authors:  Yanyan Li; Xiaoxiao Ma; Zhenwei Wei; Xiaoyun Gong; Chengdui Yang; Sichun Zhang; Xinrong Zhang
Journal:  J Am Soc Mass Spectrom       Date:  2015-05-07       Impact factor: 3.109

2.  Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics.

Authors:  F G Hayden; H E Hoffman; D A Spyker
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191

Review 3.  Clinical pharmacokinetics of amantadine hydrochloride.

Authors:  F Y Aoki; D S Sitar
Journal:  Clin Pharmacokinet       Date:  1988-01       Impact factor: 6.447
  3 in total

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