Literature DB >> 1233080

Augmentation of cytotoxic drug action and X-irradiation by antibodies.

R D Rubens, S Vaughan-Smith, R Dulbecco.   

Abstract

The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not.

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Year:  1975        PMID： 1233080      PMCID： PMC2024752          DOI： 10.1038/bjc.1975.234

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  5 in total

1.  Augmentation of cytotoxic drug action by antibodies directed at cell surface.

Authors:  R D Rubens; R Dulbecco
Journal:  Nature       Date:  1974-03-01       Impact factor: 49.962

2.  Radiosensitization of Ehrlich ascites tumour cells by a specific antibody.

Authors:  T Ghose; M Cerini
Journal:  Nature       Date:  1969-06-07       Impact factor: 49.962

Review 3.  Short review. Prospects for cancer immunochemotherapy.

Authors:  R D Rubens
Journal:  Cancer Treat Rev       Date:  1974-12       Impact factor: 12.111

4.  Proceedings: Mechanism of action studies with IRCF 159: effects on the growth and morphology of BHK-21S cells.

Authors:  T C Stephens; A M Creighton
Journal:  Br J Cancer       Date:  1974-01       Impact factor: 7.640

5.  Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies.

Authors:  D A Davies; S Buckham; A J Manstone
Journal:  Br J Cancer       Date:  1974-10       Impact factor: 7.640
  5 in total
  3 in total

1.  Regression of human melanoma xenografts in nude mice injected with methotrexate linked to monoclonal antibody 225.28 to human high molecular weight-melanoma associated antigen.

Authors:  T Ghose; S Ferrone; A H Blair; Y Kralovec; M Temponi; M Singh; M Mammen
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

2.  Influence of C. parvum on the effectiveness of passive serotherapy in the control of the EL4 lymphoma in C57BL/6 mice.

Authors:  G J O'Neill; N Stebbing
Journal:  Br J Cancer       Date:  1980-02       Impact factor: 7.640

3.  Antibody-induced changes in levels of cyclic adenosine monophosphate in leukaemic lymphocytes.

Authors:  M Virji; G T Stevenson
Journal:  Br J Cancer       Date:  1979-04       Impact factor: 7.640
  3 in total

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