Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Applications of microarrays in the pharmaceutical industry.

Literature DB >> 12324258

Applications of microarrays in the pharmaceutical industry.

Abstract

Microarrays provide the ability to measure the expression of thousands of genes in parallel. From target discovery through to uses in the clinic, microarrays are having an enormous impact on research in the pharmaceutical industry. In particular, microarrays have applications in genome annotation, they contribute to improving our disease understanding and can be used in the drug development pipeline to improve selection of biological targets and lead compounds.

Mesh：

Year: 2002 PMID： 12324258 DOI： 10.1016/s1471-4892(02)00207-2

Source DB: PubMed Journal: Curr Opin Pharmacol ISSN： 1471-4892 Impact factor: 5.547

Keyword Cloud
Cited

6 in total

1. Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells.

Authors: Pratik Jaluria; Michael Betenbaugh; Konstantinos Konstantopoulos; Bryan Frank; Joseph Shiloach
Journal: Metab Eng Date: 2006-12-13 Impact factor: 9.783

2. Sensing lectin-glycan interactions using lectin super-microarrays and glycans labeled with dye-doped silica nanoparticles.

Authors: Xin Wang; Elena Matei; Lingquan Deng; Leonardus Koharudin; Angela M Gronenborn; Olof Ramström; Mingdi Yan
Journal: Biosens Bioelectron Date: 2013-03-21 Impact factor: 10.618

3. A framework to identify gene expression profiles in a model of inflammation induced by lipopolysaccharide after treatment with thalidomide.

Authors: Renata T Paiva; Alessandra M Saliba; Tatiana O Fulco; Jorgenilce de Souza Sales; Daniel Serra de Carvalho; Elizabeth P Sampaio; Ulisses G Lopes; Euzenir N Sarno; Flavio F Nobre
Journal: BMC Res Notes Date: 2012-06-13

Applications of microarrays in the pharmaceutical industry.

1. Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells.

2. Sensing lectin-glycan interactions using lectin super-microarrays and glycans labeled with dye-doped silica nanoparticles.

3. A framework to identify gene expression profiles in a model of inflammation induced by lipopolysaccharide after treatment with thalidomide.

4. A perspective on microarrays: current applications, pitfalls, and potential uses.

5. DNA microarrays in herbal drug research.

6. Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology.