Literature DB >> 12324248

Antibiotic resistance - is resistance detected by surveillance relevant to predicting resistance in the clinical setting?

James A Karlowsky1, Daniel F Sahm.   

Abstract

Local, regional, national and global surveillance initiatives have several important functions, which include identifying shifts in antibiotic resistance, detecting the emergence of new resistance mechanisms and monitoring the impact of changes made to empiric prescribing, infection control and public health guidelines. Although the need for surveillance is indubitable and its use in the treatment of individual patients important, it cannot unequivocally predict outcomes in patients with infections. Treatment regimens for individual patients with suspected or demonstrated infections should be developed following consideration of symptoms, laboratory findings and relevant medical history, and in the context of appropriate local and widespread antibiotic resistance trends.

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Year:  2002        PMID: 12324248     DOI: 10.1016/s1471-4892(02)00193-5

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN: 1471-4892            Impact factor:   5.547


  1 in total

1.  In vitro susceptibilities of gram-negative bacteria isolated from hospitalized patients in four European countries, Canada, and the United States in 2000-2001 to expanded-spectrum cephalosporins and comparator antimicrobials: implications for therapy.

Authors:  Richard P Wenzel; Daniel F Sahm; Clyde Thornsberry; Deborah C Draghi; Mark E Jones; James A Karlowsky
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191

  1 in total

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