Literature DB >> 12324184

Fetal magnetocardiography in the investigation of congenital heart defects.

Christiane Kähler1, Ekkehard Schleussner, Barbara Grimm, Uwe Schneider, Jens Haueisen, Lothar Vogt, Hans-Joachim Seewald.   

Abstract

OBJECTIVES: To investigate the changes of the fetal magnetocardiography (FMCG), a new noninvasive diagnostic tool in the analysis of electrophysiologic changes of the heart, in cases of congenital heart defect (CHD).
METHODS: The FMCG was analysed and compared to the postnatal ECG in eight cases of CHD: atrial septal defect ASDII (three cases), a combination of atrioventricular-septal-defect (AVSD) and Tetralogy of Fallot (TOF) (one case ), complete transposition of great arteries (d-TGA) (two cases), coarctation of aorta (COA) (one case), stenosis of the pulmonary artery (PS) and right ventricular hypoplasia (one case).
RESULTS: (1) The following FMCG changes were observed: a split R-wave (AVSD/TOF, ASDII), prolongation of QRS complex (COA, PS). (2) The notch of the R-wave could not be observed in the newborn with AVSD/TOF. (3) Neither the fetal FMCG nor the neonatal ECG revealed any changes in the cases of d-TGA. (4) All other neonatal ECGs were corresponding to the FMCG.
CONCLUSIONS: The FMCG can unearth changes of the cardiac electrophysiologic activity in the case of CHD. The method provides additional information concerning the effect of a CHD on the cardiac conductory system. As in the neonate, the FMCG changes do not reflect the severity of the CHD. FMCG cannot serve as a primary diagnostic tool in the case of CHD as compared to echocardiography.

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Year:  2002        PMID: 12324184     DOI: 10.1016/s0378-3782(02)00041-5

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN: 0378-3782            Impact factor:   2.079


  3 in total

Review 1.  Diagnosis and treatment of fetal arrhythmia.

Authors:  Annette Wacker-Gussmann; Janette F Strasburger; Bettina F Cuneo; Ronald T Wakai
Journal:  Am J Perinatol       Date:  2014-05-23       Impact factor: 1.862

2.  Evaluation of Abdominal Fetal Electrocardiography in Early Intrauterine Growth Restriction.

Authors:  Clarissa L Velayo; Kiyoe Funamoto; Joyceline Noemi I Silao; Yoshitaka Kimura; Kypros Nicolaides
Journal:  Front Physiol       Date:  2017-06-26       Impact factor: 4.566

3.  Investigating myocardial performance in normal and sick fetuses by abdominal Doppler signal derived indices.

Authors:  Ahsan H Khandoker; Haitham M Al-Angari; Faezeh Marzbanrad; Yoshitaka Kimura
Journal:  Curr Res Physiol       Date:  2021-02-05
  3 in total

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