Literature DB >> 12323354

Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris.

Geoff P Lin Cereghino1, Joan Lin Cereghino, Christine Ilgen, James M Cregg.   

Abstract

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

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Year:  2002        PMID： 12323354     DOI： 10.1016/s0958-1669(02)00330-0

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  101 in total

1.  Efficient secretion of inulin fructotransferase in Pichia pastoris using the formaldehyde dehydrogenase 1 promoter.

Authors:  Rongrong Zhan; Wanmeng Mu; Bo Jiang; Liuming Zhou; Tao Zhang
Journal:  J Ind Microbiol Biotechnol       Date:  2014-11-04       Impact factor: 3.346

2.  Engineering of Yeast Glycoprotein Expression.

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Review 3.  Monoclonal antibody form and function: manufacturing the right antibodies for treating drug abuse.

Authors:  Eric Peterson; S Michael Owens; Ralph L Henry
Journal:  AAPS J       Date:  2006-05-26       Impact factor: 4.009

4.  Multimeric HCV E2 protein obtained from Pichia pastoris cells induces a strong immune response in mice.

Authors:  Gillian Martínez-Donato; Yanelis Capdesuñer; Nelson Acosta-Rivero; Armando Rodríguez; Juan Morales-Grillo; Eduardo Martínez; Marleny González; Julio C Alvarez-Obregon; Santiago Dueñas-Carrera
Journal:  Mol Biotechnol       Date:  2007-03       Impact factor: 2.695

5.  Dunaliella as an attractive candidate for molecular farming.

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Journal:  Mol Biol Rep       Date:  2009-11-27       Impact factor: 2.316

6.  Cloning and Expression of Iranian Turkmen-thoroughbred Horse Follicle Stimulating Hormone in Pichia pastoris.

Authors:  Zahra Elyasi Gorji; Amir Amiri-Yekta; Hamid Gourabi; Saeed Hassani; Nayeralsadat Fatemi; Saeed Zerehdaran; Faezeh Vakhshiteh; Mohammad Hossein Sanati
Journal:  Iran J Biotechnol       Date:  2015-06       Impact factor: 1.671

Review 7.  Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells.

Authors:  Aleš Berlec; Borut Strukelj
Journal:  J Ind Microbiol Biotechnol       Date:  2013-02-06       Impact factor: 3.346

8.  A simple Pichia pastoris fermentation and downstream processing strategy for making recombinant pandemic Swine Origin Influenza a virus Hemagglutinin protein.

Authors:  T N Athmaram; Anil Kumar Singh; Shweta Saraswat; Saurabh Srivastava; Princi Misra; M Kameswara Rao; N Gopalan; P V L Rao
Journal:  J Ind Microbiol Biotechnol       Date:  2012-12-18       Impact factor: 3.346

9.  Expression of alkaline sphingomyelinase in yeast cells and anti-inflammatory effects of the expressed enzyme in a rat colitis model.

Authors:  David Andersson; Knut Kotarsky; Jun Wu; William Agace; Rui-Dong Duan
Journal:  Dig Dis Sci       Date:  2008-11-07       Impact factor: 3.199

10.  Assay and heterologous expression in Pichia pastoris of plant cell wall type-II membrane anchored glycosyltransferases.

Authors:  Bent Larsen Petersen; Jack Egelund; Iben Damager; Kirsten Faber; Jacob Krüger Jensen; Zhang Yang; Eric Paul Bennett; Henrik Vibe Scheller; Peter Ulvskov
Journal:  Glycoconj J       Date:  2009-12       Impact factor: 2.916
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