| Literature DB >> 12323057 |
Barry M Trost1, Vince S C Yeh.
Abstract
Boronolide was synthesized stereoselectively from hydroxyacetylfuran 5 and valeraldehyde 6 using a novel dizinc aldol catalyst. Ring closing metathesis provides the lactone ring. The synthesis requires 12 steps and proceeds in 26% overall yield. [reaction: see text]Entities:
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Year: 2002 PMID: 12323057 DOI: 10.1021/ol026665i
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005