Literature DB >> 12323028

Modular synthesis of amine-functionalized oxazolines.

Sridhar Rajaram1, Matthew S Sigman.   

Abstract

Substituted oxazoline amines have been prepared in high yield from beta-amino alcohols and Fmoc-protected alpha-amino acids using CCl(4), PPh(3), and Hünig's base in a one-pot procedure followed by base-mediated deprotection. [reaction: see text]

Entities:  

Year:  2002        PMID： 12323028     DOI： 10.1021/ol0264758

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Oxazolines as Dual-Function Traceless Chromophores and Chiral Auxiliaries: Enantioselective Photoassisted Synthesis of Polyheterocyclic Ketones.

Authors:  Olga A Mukhina; Andrei G Kutateladze
Journal:  J Am Chem Soc       Date:  2016-02-16       Impact factor: 15.419

2.  Predicting and optimizing asymmetric catalyst performance using the principles of experimental design and steric parameters.

Authors:  Kaid C Harper; Matthew S Sigman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-24       Impact factor: 11.205

3.  Sulfur(iv)-mediated umpolung α-heterofunctionalization of 2-oxazolines.

Authors:  Qifeng Zhang; Yuchen Liang; Ruiqi Li; Ziyi Huang; Lichun Kong; Peng Du; Bo Peng
Journal:  Chem Sci       Date:  2022-04-09       Impact factor: 9.969

4.  Synthesis of 2-Oxazolines from Ring Opening Isomerization of 3-Amido-2-Phenyl Azetidines.

Authors:  Xin Zhou; Baiyi Mao; Zhanbin Zhang
Journal:  Molecules       Date:  2021-02-06       Impact factor: 4.411

5.  Synthesis of D-fructose-derived spirocyclic 2-substituted-2-oxazoline ribosides.

Authors:  Madhuri Vangala; Ganesh P Shinde
Journal:  Beilstein J Org Chem       Date:  2015-11-24       Impact factor: 2.883
  5 in total

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