Literature DB >> 123156

Diphenylhydantoin. Blocking of levodopa effects.

J S Mendez, G C Cotzias, I Mena, P S Papavasiliou.   

Abstract

Diphenylhydantoin (DPH) diminished the therapeutic effects of levodopa both in patients with parkinsonism and in patients with chronic manganese poisoning, as well as the levodopa-dependent dyskinesia for which the former were selected. In patients with Huntington chorea, it enhanced chorea and mental agitation and, thus, failed to conform with the postulated pharmacological reciprocity between Parkinson disease and Huntington chorea. These findings are in agreement with experiments done in animals in which DPH blocked a neuronal response to dopamine.

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Year:  1975        PMID： 123156     DOI： 10.1001/archneur.1975.00490430066011

Source DB:  PubMed          Journal:  Arch Neurol        ISSN： 0003-9942


  9 in total

Review 1.  Medication-Induced Tardive Dyskinesia: A Review and Update.

Authors:  Elyse M Cornett; Matthew Novitch; Alan David Kaye; Vijay Kata; Adam M Kaye
Journal:  Ochsner J       Date:  2017

2.  Neuroleptic malignant syndrome induced by phenytoin in a patient with drug-induced Parkinsonism.

Authors:  Hae-Won Shin; Young Chul Youn
Journal:  Neurol Sci       Date:  2014-05-29       Impact factor: 3.307

3.  Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.

Authors:  D Chadwick; E H Reynolds; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1976-12       Impact factor: 10.154

4.  Phenytoin-induced orofacial dyskinesia. A case report.

Authors:  M Yoshida; S Yamada; Y Ozaki; T Nakanishi
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

Review 5.  Antiseizure Drugs and Movement Disorders.

Authors:  Michel Sáenz-Farret; Marina A J Tijssen; Dawn Eliashiv; Robert S Fisher; Kapil Sethi; Alfonso Fasano
Journal:  CNS Drugs       Date:  2022-07-21       Impact factor: 6.497

6.  Antiparkinsonian Agents : Clinically Significant Drug Interactions and Adverse Effects, and Their Management.

Authors:  A Dalvi; B Ford
Journal:  CNS Drugs       Date:  1998-04       Impact factor: 5.749

7.  Clinical and experimental studies of phenytoin-induced hyperkinesias.

Authors:  P A Nausieda; W C Koller; W J Weiner; H L Klawans
Journal:  J Neural Transm       Date:  1979       Impact factor: 3.575

8.  Dopaminomimetic action of diphenylhydantoin in rat striatum: effect on homovanillic acid and cyclic AMP levels.

Authors:  V Lepore; N Di Reda; G Defazio; D Pedone; A Giovine; C Lanzi; B Tartaglione; P Livrea
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

Review 9.  Acute dystonia induced by neuroleptic drugs.

Authors:  N M Rupniak; P Jenner; C D Marsden
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530
  9 in total

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