Literature DB >> 1231096

[Progressive polyploidy in mouse liver following repeated hepatectomy].

V M Faktor, I V Uryvaeva.   

Abstract

Mouse liver regeneration after partial hepatectomy results in sharp changes of ploidy classes towards the increase of high ploidy cells and the decrease low ploidy ones. These changes retain during three months. Each following partial hepatectomy (till 3 times) intensifies the hepatocyte polyploidy with appearance of cells with 32--64 ploidy nuclei. The cell polyploidization stimulated by repeated regenerations is similar to that observed in normal postnatal liver growth.

Entities:  

Mesh：

Year:  1975        PMID： 1231096

Source DB:  PubMed          Journal:  Tsitologiia        ISSN： 0041-3771


  7 in total

Review 1.  The origins and functions of hepatic polyploidy.

Authors:  Shuyuan Zhang; Yu-Hsuan Lin; Branden Tarlow; Hao Zhu
Journal:  Cell Cycle       Date:  2019-05-26       Impact factor: 4.534

Review 2.  Polyploidy in liver development, homeostasis and disease.

Authors:  Romain Donne; Maëva Saroul-Aïnama; Pierre Cordier; Séverine Celton-Morizur; Chantal Desdouets
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2020-04-02       Impact factor: 46.802

3.  Aneuploidy as a mechanism for stress-induced liver adaptation.

Authors:  Andrew W Duncan; Amy E Hanlon Newell; Weimin Bi; Milton J Finegold; Susan B Olson; Arthur L Beaudet; Markus Grompe
Journal:  J Clin Invest       Date:  2012-08-06       Impact factor: 14.808

4.  p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver.

Authors:  Svitlana Kurinna; Sabrina A Stratton; Zeynep Coban; Jill M Schumacher; Markus Grompe; Andrew W Duncan; Michelle Craig Barton
Journal:  Hepatology       Date:  2013-02-15       Impact factor: 17.425

5.  The ploidy conveyor of mature hepatocytes as a source of genetic variation.

Authors:  Andrew W Duncan; Matthew H Taylor; Raymond D Hickey; Amy E Hanlon Newell; Michelle L Lenzi; Susan B Olson; Milton J Finegold; Markus Grompe
Journal:  Nature       Date:  2010-09-22       Impact factor: 49.962

6.  Single-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes.

Authors:  Francesca Faggioli; Paolo Vezzoni; Cristina Montagna
Journal:  PLoS One       Date:  2011-10-12       Impact factor: 3.240

7.  Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver.

Authors:  Heng Lin; Yen-Sung Huang; Hsu-Wen Chao; Jean-Michel Fustin; Masao Doi; Huatao Chen; Hui-Huang Lai; Shu-Hui Lin; Yen-Lurk Lee; Pei-Chih King; Hsien-San Hou; Hao-Wen Chen; Pei-Yun Young
Journal:  Nat Commun       Date:  2021-01-28       Impact factor: 14.919
  7 in total

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