Postoperative nausea and emesis.

Watcha and White [51] have made recommendations for antiemetic therapy and prophylaxis based on published peer-reviewed studies. They range from no prophylaxis for patients at low risk to "multimodal" antiemetic therapy for those at the highest risk (Fig. 1) [10]. Recommendations for rescue therapy of breakthrough PONV are also provided. With this approach, it should be possible [figure: see text] to individualize prophylaxis and rescue therapy to achieve an optimal cost-effective management strategy for this uncomfortable postoperative complication.