Literature DB >> 12297409

T helper cells, IL-2 and the generation of cytotoxic T-cell responses.

Thomas R Malek.   

Abstract

CD8 T-cell immunity is thought to require helper activity derived from CD4 T cells. Nevertheless, under some circumstances, effective CD8-dependent T-cell responses occur in vivo without CD4 T-cell help. Several recent papers help to explain this paradox and lead to a refined view concerning the role of T helper cells and interleukin-2 receptor signaling in the production of cytotoxic T lymphocytes.

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Year:  2002        PMID： 12297409     DOI： 10.1016/s1471-4906(02)02308-6

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  16 in total

1.  In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8(+) T cell responses.

Authors:  Christoph Esslinger; Laurence Chapatte; Daniela Finke; Isabelle Miconnet; Philippe Guillaume; Frédéric Lévy; H Robson MacDonald
Journal:  J Clin Invest       Date:  2003-06       Impact factor: 14.808

2.  CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses.

Authors:  Hiroyoshi Nishikawa; Takuma Kato; Koji Tanida; Atsunori Hiasa; Isao Tawara; Hiroaki Ikeda; Yoshinori Ikarashi; Hiro Wakasugi; Mitchell Kronenberg; Toshinori Nakayama; Masaru Taniguchi; Kagemasa Kuribayashi; Lloyd J Old; Hiroshi Shiku
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-28       Impact factor: 11.205

3.  Assessment by flow cytometry of cytokine production in malnourished children.

Authors:  Leonor Rodríguez; Cristina González; Luis Flores; Luis Jiménez-Zamudio; Jaime Graniel; Rocío Ortiz
Journal:  Clin Diagn Lab Immunol       Date:  2005-04

4.  Expression of cytokine mRNA in lymphocytes of malnourished children.

Authors:  Haydeé González-Martínez; Leonor Rodríguez; Oralia Nájera; David Cruz; Angel Miliar; Aarón Domínguez; Fausto Sánchez; Jaime Graniel; María Cristina González-Torres
Journal:  J Clin Immunol       Date:  2008-05-22       Impact factor: 8.317

5.  Protein malnutrition alters spleen cell proliferation and IL-2 and IL-10 production by affecting the STAT-1 and STAT-3 balance.

Authors:  Alexandra Siqueira Mello; Dalila Cunha de Oliveira; Bruna Bizzarro; Anderson Sá-Nunes; Araceli Aparecida Hastreiter; Jackeline Soares de Oliveira Beltran; José Guilherme Xavier; Primavera Borelli; Ricardo Ambrósio Fock
Journal:  Inflammation       Date:  2014-12       Impact factor: 4.092

6.  An immunogenic phenotype in paternal antigen-specific CD8+ T cells at embryo implantation elicits later fetal loss in mice.

Authors:  Lachlan M Moldenhauer; Kerrilyn R Diener; John D Hayball; Sarah A Robertson
Journal:  Immunol Cell Biol       Date:  2017-05-22       Impact factor: 5.126

Review 7.  Cytokine production associated with smallpox vaccine responses.

Authors:  Whitney L Simon; Hannah M Salk; Inna G Ovsyannikova; Richard B Kennedy; Gregory A Poland
Journal:  Immunotherapy       Date:  2014       Impact factor: 4.196

8.  Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency.

Authors:  Monica Vaccari; Joseph Mattapallil; Kaimei Song; Wen-Po Tsai; Anna Hryniewicz; David Venzon; Maurizio Zanetti; Keith A Reimann; Mario Roederer; Genoveffa Franchini
Journal:  J Virol       Date:  2008-07-30       Impact factor: 5.103

9.  AFP-specific CD4+ helper T-cell responses in healthy donors and HCC patients.

Authors:  Viktoria N Evdokimova; Yang Liu; Douglas M Potter; Lisa H Butterfield
Journal:  J Immunother       Date:  2007 May-Jun       Impact factor: 4.456

10.  Impact of cytokine and cytokine receptor gene polymorphisms on cellular immunity after smallpox vaccination.

Authors:  Inna G Ovsyannikova; Iana H Haralambieva; Richard B Kennedy; V Shane Pankratz; Robert A Vierkant; Robert M Jacobson; Gregory A Poland
Journal:  Gene       Date:  2012-08-23       Impact factor: 3.688
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