Literature DB >> 122802

Synthesis of chlorozotocin, the 2-chloroethyl analog of the anticancer antibiotic streptozotocin.

T P Johnston, G S McCaleb, J A Montgomery.   

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Year:  1975        PMID： 122802     DOI： 10.1021/jm00235a023

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  12 in total

1.  Comparative pharmacology of three new nitrosourea analogues: RFCNU, RPCNU, and chlorozotocin. I. Oncostatic effects in mice.

Authors:  M Hayat; C Bourut; E Chenu; J L Montero; J L Imbach; J S MacDonald; G Mathé
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

Review 2.  DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds.

Authors:  G Eisenbrand; N Müller; E Denkel; W Sterzel
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

3.  Antitumor activity of a nitrosourea derivative, CNUA, on murine tumors.

Authors:  K Edanami; K Komiyama; T Kuroda; I Umezawa
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

4.  In vitro comparative studies of the myelotoxicity and antitumor activity of 6-[bis-(2-chloroethyl)-amino]-6-deoxy-D-glucose versus melphalan utilizing the CFU-C and HTSCA assays.

Authors:  P Lazarus; M Dufour; G Isabel; L C Panasci
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

5.  Chlorozotocin. Mechanism of reduced bone marrow toxicity in mice.

Authors:  L C Panasci; D Green; P S Schein
Journal:  J Clin Invest       Date:  1979-10       Impact factor: 14.808

6.  Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.

Authors:  W J Zeller; G Eisenbrand; H H Fiebig
Journal:  J Cancer Res Clin Oncol       Date:  1979-09       Impact factor: 4.553

7.  Cytostatic action of two nitrosoureas derived from cysteamine.

Authors:  C Bourut; E Chenu; D Godenèche; J C Madelmont; R Maral; G Mathé; G Meyniel
Journal:  Br J Pharmacol       Date:  1986-11       Impact factor: 8.739

8.  New derivatives of CNC-amino acids and -oligopeptides: experimental antitumor activity.

Authors:  W J Zeller
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

9.  Phase II study of chlorozotocin in islet cell carcinoma. A southwest Oncology Group study.

Authors:  R M Bukowski; J D McCracken; S P Balcerzak; C J Fabian
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333

10.  Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential.

Authors:  G Eisenbrand; H H Fiebig; W J Zeller
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1976-08-30
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