Limb malformations in the cloverleaf skull anomaly.

An Egyptian child with the rare cloverleaf skull anomaly had associated limb malformations which suggested that he had the Pfeiffer syndrome with severe skull involvement. The cloverleaf skull is an anomaly which may occur as a part of several syndromes. Careful study of skeletal changes, particularly limb malformations, may be the clue to the different syndromes with which cloverleaf skull may be associated.