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Literature DB >> 1227499

Luteal 20alpha-hydroxy steroid dehydrogenase and the formation of delta4-3-oxo steroids in the rat after weaning or treatment with 2-bromo-alpha-ergocryptine during lactation.

Abstract

Natural or early weaning of rat litters caused an increased activity of maternal luteal 20alpha-hydroxy steroid dehydrogenase and a decreased release of delta4-3-oxo steroids in vitro. 2. Compound CB-154 (2-bromo-alpha-ergocryptine) caused an increase of 20alpha-hydroxy steroid dehydrogenase activity in mid-lactation but not in early lactation. 3. Prolaction did not prevent these increases in enzyme activity.

Entities: Chemical Gene Species

Keywords: Alkaloids; Animals, Laboratory; Biology; Clinical Research; Endocrine System; Ergot Alkaloids; Fetus; Hormones; In Vitro; Ingredients And Chemicals; Lactation; Maternal Physiology; Metabolic Effects; Organic Chemicals; Physiology; Pituitary Hormones; Pregnancy; Prolactin; Reproduction; Research Methodology; Steroid Metabolic Effects

Mesh：

Substances：

Year: 1975 PMID： 1227499 PMCID： PMC1172496 DOI： 10.1042/bj1520445

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

12 in total

4. Ovarian progestin secretion in lactating rats: effect of intrabursal injection of prolactin antiserum, prolactin and LH.

Authors: K Yoshinaga
Journal: Endocrinology Date: 1974-03 Impact factor: 4.736

5. Progesterone and pregn-4-en-20 alpha-ol-3-one in ovarian venous blood during various reproductive states in the rat.

Authors: I Hashimoto; D M Henricks; L L Anderson; R M Melampy
Journal: Endocrinology Date: 1968-02 Impact factor: 4.736

6. Studies on the mechanism of nidation. XXXI. Failure of ergocornine to interrupt gastation in the rat in the presence of foetal placenta.

Authors: E S Kisch; M C Shelesnyak
Journal: J Reprod Fertil Date: 1968-04

7. Progesterone catabolism in the rat ovary: a regulatory mechanism for progestational potency during pregnancy.

Authors: W G Wiest; W R Kidwell; K Balogh
Journal: Endocrinology Date: 1968-04 Impact factor: 4.736

8. Induction of 20alpha-hydroxysteroid dehydrogenase in rat corpora lutea by pharmacological blockade of pituitary prolactin secretion.

Authors: S A Lamprecht; H R Lindner; J F Strauss
Journal: Biochim Biophys Acta Date: 1969-07-29

9. Inhibition of lactation and prolactin secretion in rats by ergot alkaloids.

Authors: C J Shaar; J A Clemens
Journal: Endocrinology Date: 1972-01 Impact factor: 4.736

10. Hormonal control of Luteal 20alpha-Hydroxy steroid dehydrogenase and delta5-3beta-hydroxy steroid dehydrogenase during luteolysis in the pregnant rat.

Authors: R G Rodway; N J Kuhn
Journal: Biochem J Date: 1975-12 Impact factor: 3.857

2 in total

1. A proposed sequence of hormones controlling the induction of luteal 20alpha-hydroxy steroid dehydrogenase and progesterone withdrawal in the late-pregnant rat.

Authors: D H Smith; N J Kuhn
Journal: Biochem J Date: 1976-12-15 Impact factor: 3.857

2. Hormonal control of Luteal 20alpha-Hydroxy steroid dehydrogenase and delta5-3beta-hydroxy steroid dehydrogenase during luteolysis in the pregnant rat.