BACKGROUND: Psoriasis affects 7 million people in the United States, causing substantial cost, social stigma, and disability. OBJECTIVE: The purpose of this study was to evaluate the health effects of skin disease by comparing psoriasis to other primary medical disorders using 3 different scales of health-related quality of life. METHODS: A self-administered questionnaire consisting of 3 health-related quality of life measures was given sequentially to 35 eligible patients with psoriasis presenting to the Dermatology Branch of the National Cancer Institute (NCI) for an investigational therapeutic protocol. RESULTS: All patients (100%) agreed to participate. The median Psoriasis Area and Severity Index (PASI) score was 13.0. Overall, 82.9% at least often felt the need to hide their psoriasis, and 74.3% claimed their self-confidence was at least often affected by their psoriasis. The median EQ-5D health state utility score was 13.0% less than healthy individuals (P <.001). On the SF-36, the mean general health score was 13.2% less (P =.005) and the median social functioning score 18.7% less (P =.005) than that of patients with no chronic conditions. CONCLUSION: Individuals with psoriasis are significantly affected in their health state utility, perception of general health, and social functioning when compared with individuals without chronic disease and those with certain primary medical conditions.
BACKGROUND:Psoriasis affects 7 million people in the United States, causing substantial cost, social stigma, and disability. OBJECTIVE: The purpose of this study was to evaluate the health effects of skin disease by comparing psoriasis to other primary medical disorders using 3 different scales of health-related quality of life. METHODS: A self-administered questionnaire consisting of 3 health-related quality of life measures was given sequentially to 35 eligible patients with psoriasis presenting to the Dermatology Branch of the National Cancer Institute (NCI) for an investigational therapeutic protocol. RESULTS: All patients (100%) agreed to participate. The median Psoriasis Area and Severity Index (PASI) score was 13.0. Overall, 82.9% at least often felt the need to hide their psoriasis, and 74.3% claimed their self-confidence was at least often affected by their psoriasis. The median EQ-5D health state utility score was 13.0% less than healthy individuals (P <.001). On the SF-36, the mean general health score was 13.2% less (P =.005) and the median social functioning score 18.7% less (P =.005) than that of patients with no chronic conditions. CONCLUSION: Individuals with psoriasis are significantly affected in their health state utility, perception of general health, and social functioning when compared with individuals without chronic disease and those with certain primary medical conditions.
Authors: Ivan Grozdev; Douglas Kast; Lauren Cao; Diana Carlson; Prasad Pujari; Brian Schmotzer; Denise Babineau; Elizabeth Kern; Thomas McCormick; Kevin D Cooper; Neil J Korman Journal: J Invest Dermatol Date: 2011-12-29 Impact factor: 8.551
Authors: Narasimharao Bhagavathula; Kamalakar C Nerusu; Gary J Fisher; Gao Liu; Archana B Thakur; Lorraine Gemmell; Shankar Kumar; Zenghai H Xu; Paul Hinton; Naoya Tsurushita; Nicholas F Landolfi; John J Voorhees; James Varani Journal: Am J Pathol Date: 2005-04 Impact factor: 4.307
Authors: A Kavanaugh; C Antoni; G G Krueger; S Yan; M Bala; L T Dooley; A Beutler; C Guzzo; D Gladman Journal: Ann Rheum Dis Date: 2005-08-11 Impact factor: 19.103
Authors: Charles G Helmick; Hyewon Lee-Han; Shawn C Hirsch; Tiffany L Baird; Christopher L Bartlett Journal: Am J Prev Med Date: 2014-04-18 Impact factor: 5.043
Authors: Jina Chung; Kristina Callis Duffin; Junko Takeshita; Daniel B Shin; Gerald G Krueger; Andrew D Robertson; Andrea B Troxel; Abby S Van Voorhees; Emily Edson-Heredia; Joel M Gelfand Journal: J Am Acad Dermatol Date: 2014-06-02 Impact factor: 11.527
Authors: Jean-Eric Tarride; Natasha Burke; Matthias Bischof; Robert B Hopkins; Linda Goeree; Kaitryn Campbell; Feng Xie; Daria O'Reilly; Ron Goeree Journal: Health Qual Life Outcomes Date: 2010-01-27 Impact factor: 3.186
Authors: Dennis A Revicki; Alan Menter; Steven Feldman; Miriam Kimel; Neesha Harnam; Mary K Willian Journal: Health Qual Life Outcomes Date: 2008-10-02 Impact factor: 3.186