Literature DB >> 12270958

Agrin in the developing CNS: new roles for a synapse organizer.

Stephan Kröger1, Jörn E Schröder.   

Abstract

The heparan sulfate proteoglycan agrin is responsible for the formation, maintenance, and regeneration of the neuromuscular junction. In the central nervous system, agrin is widely expressed and concentrated at interneuronal synapses, but its function during synaptogenesis remains controversial. Instead, evidence for additional functions of agrin during axonal growth, establishment of the blood-brain barrier, and Alzheimer's disease is accumulating.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12270958     DOI： 10.1152/nips.01390.2002

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  10 in total

1.  The process-inducing activity of transmembrane agrin requires follistatin-like domains.

Authors:  Elmar Porten; Beate Seliger; Verena A Schneider; Stefan Wöll; Daniela Stangel; Rene Ramseger; Stephan Kröger
Journal:  J Biol Chem       Date:  2009-11-25       Impact factor: 5.157

Review 2.  The vascular basement membrane in the healthy and pathological brain.

Authors:  Maj S Thomsen; Lisa J Routhe; Torben Moos
Journal:  J Cereb Blood Flow Metab       Date:  2017-07-28       Impact factor: 6.200

Review 3.  Basement Membrane Changes in Ischemic Stroke.

Authors:  Minkyung Kang; Yao Yao
Journal:  Stroke       Date:  2020-03-03       Impact factor: 7.914

Review 4.  The Role of Extracellular Matrix Components in the Spreading of Pathological Protein Aggregates.

Authors:  Edoardo Moretto; Skye Stuart; Sunaina Surana; Jose Norberto S Vargas; Giampietro Schiavo
Journal:  Front Cell Neurosci       Date:  2022-04-29       Impact factor: 6.147

5.  Agrin expression during synaptogenesis induced by traumatic brain injury.

Authors:  M Cristina Falo; Thomas M Reeves; Linda L Phillips
Journal:  J Neurotrauma       Date:  2008-07       Impact factor: 5.269

6.  Transmembrane form agrin-induced process formation requires lipid rafts and the activation of Fyn and MAPK.

Authors:  Rene Ramseger; Robin White; Stephan Kröger
Journal:  J Biol Chem       Date:  2009-01-12       Impact factor: 5.157

7.  Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain.

Authors:  Christine O Sallum; Richard A Kammerer; Andrei T Alexandrescu
Journal:  Biochemistry       Date:  2007-07-25       Impact factor: 3.162

8.  Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

Authors:  Marta Del Campo Milan; Leah Zuroff; Connie R Jimenez; Philip Scheltens; Charlotte E Teunissen
Journal:  Alzheimers Dement (Amst)       Date:  2015-03-29

9.  A Novel Egr-1-Agrin Pathway and Potential Implications for Regulation of Synaptic Physiology and Homeostasis at the Neuromuscular Junction.

Authors:  Ryen MacDonald; Sebastien Barbat-Artigas; Chulmin Cho; Huashan Peng; Jijun Shang; Ayman Moustaine; Salvatore Carbonetto; Richard Robitaille; Lorraine E Chalifour; Hemant Paudel
Journal:  Front Aging Neurosci       Date:  2017-08-03       Impact factor: 5.750

10.  The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions.

Authors:  Esther Steiner; Gaby U Enzmann; Ruth Lyck; Shuo Lin; Markus A Rüegg; Stephan Kröger; Britta Engelhardt
Journal:  Cell Tissue Res       Date:  2014-08-09       Impact factor: 5.249
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.