Literature DB >> 12270189

Protein degradation with photoactivated enediyne-amino acid conjugates.

Gary Plourde1, Ahmed El-Shafey, Farid S Fouad, Ajay S Purohit, Graham B Jones.   

Abstract

A series of photoactivated enediynes was prepared, and successfully employed for the selective degradation of target proteins.

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Year:  2002        PMID： 12270189     DOI： 10.1016/s0960-894x(02)00618-2

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Triggering of the Bergman cyclization by photochemical ring contraction. Facile cycloaromatization of benzannulated cyclodeca-3,7-diene-1,5-diynes.

Authors:  Grigori V Karpov; Vladimir V Popik
Journal:  J Am Chem Soc       Date:  2007-03-13       Impact factor: 15.419

2.  C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy.

Authors:  Wang-Yong Yang; Boris Breiner; Serguei V Kovalenko; Chi Ben; Mani Singh; Shauna N LeGrand; Qing-Xiang Amy Sang; Geoffrey F Strouse; John A Copland; Igor V Alabugin
Journal:  J Am Chem Soc       Date:  2009-08-19       Impact factor: 15.419

3.  Two-photon photochemical generation of reactive enediyne.

Authors:  Andrei Poloukhtine; Vladimir V Popik
Journal:  J Org Chem       Date:  2006-09-15       Impact factor: 4.354
  3 in total

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