OBJECTIVES: To determine the prevalence of and the risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage in nursing home residents in the Rhine-Neckar region of southern Germany. DESIGN: Point-prevalence survey. SETTING: Forty-seven nursing homes in the region. PARTICIPANTS: All residents of the approached nursing homes who agreed to participate. METHODS: After informed consent was obtained, all participants had their nares swabbed, some personal data collected, or both. All swabs were examined for growth of MRSA. All S. aureus isolates underwent oxacillin susceptibility testing and polymerase chain reaction for demonstration of the mecA gene. All MRSA isolates were typed using pulsed-field gel electrophoresis after digestion with SmaI. RESULTS: Swabs from 3,236 nursing home residents yielded 36 MRSA strains, contributing to a prevalence rate of 1.1%. Significant risk factors for MRSA carriage in the multivariate analysis were the presence of wounds or urinary catheters, limited mobility, admission to a hospital during the preceding 3 months, or stay in a medium-size nursing home. One predominant MRSA strain could be detected in 30 of the 36 MRSA carriers. CONCLUSIONS: The prevalence of MRSA in German nursing homes is still low. These residents seemed to acquire their MRSA in the hospital and transfer it to their nursing home. Apart from well-known risk factors for the acquisition of MRSA, we identified the size of the nursing home as an independent risk factor. This might be due to an increased use of and microbials in nursing homes of a certain size.
OBJECTIVES: To determine the prevalence of and the risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage in nursing home residents in the Rhine-Neckar region of southern Germany. DESIGN: Point-prevalence survey. SETTING: Forty-seven nursing homes in the region. PARTICIPANTS: All residents of the approached nursing homes who agreed to participate. METHODS: After informed consent was obtained, all participants had their nares swabbed, some personal data collected, or both. All swabs were examined for growth of MRSA. All S. aureus isolates underwent oxacillin susceptibility testing and polymerase chain reaction for demonstration of the mecA gene. All MRSA isolates were typed using pulsed-field gel electrophoresis after digestion with SmaI. RESULTS: Swabs from 3,236 nursing home residents yielded 36 MRSA strains, contributing to a prevalence rate of 1.1%. Significant risk factors for MRSA carriage in the multivariate analysis were the presence of wounds or urinary catheters, limited mobility, admission to a hospital during the preceding 3 months, or stay in a medium-size nursing home. One predominant MRSA strain could be detected in 30 of the 36 MRSA carriers. CONCLUSIONS: The prevalence of MRSA in German nursing homes is still low. These residents seemed to acquire their MRSA in the hospital and transfer it to their nursing home. Apart from well-known risk factors for the acquisition of MRSA, we identified the size of the nursing home as an independent risk factor. This might be due to an increased use of and microbials in nursing homes of a certain size.
Authors: Robin Köck; Alexander Mellmann; Frieder Schaumburg; Alexander W Friedrich; Frank Kipp; Karsten Becker Journal: Dtsch Arztebl Int Date: 2011-11-04 Impact factor: 5.594
Authors: P Brugnaro; U Fedeli; G Pellizzer; D Buonfrate; M Rassu; C Boldrin; S G Parisi; A Grossato; G Palù; P Spolaore Journal: Infection Date: 2008-12-09 Impact factor: 3.553
Authors: C F M van der Donk; J M G A Schols; V Schneiders; K-H Grimm; E E Stobberingh Journal: Eur J Clin Microbiol Infect Dis Date: 2013-06-04 Impact factor: 3.267