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Literature DB >> 122528

Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas.

Abstract

Against sulbenicillin- and gentamicin-susceptible strains of Pseudomonas aeruginosa, SCE-129 was about 10 times more active than sulbenicillin and had a similar activity to gentamicin and dibekacin. Sulbenicillin-resistant strains of P. aeruginosa were moderately resistant to SCE-129, whether these strains were gentamicin-resistant or not. Gentamicin-resistant strains of P. aeruginosa were resistant to dibekacin but not to SCE-129. Against P. maltophilia, the minimum inhibitory concentration of SCE-129 resembled those of sulbenicillin, gentamicin, and dibekacin. Most strains of P. cepacia were moderately resistant to SCE-129 and sulbenicillin and highly resistant to gentamicin and dibekacin.

Entities: Chemical Species

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Year: 1978 PMID： 122528 PMCID： PMC352277 DOI： 10.1128/AAC.13.3.536

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. [Effect of a new antibiotic 3',4'-dideoxykanamycin B on auditory function of the guinea pig].

Authors: T Nakazawa; K Fukushima
Journal: Jpn J Antibiot Date: 1973-02

2. [Audiometric and histopathologic evaluation of ototoxicity of 3',4'-dideoxykanamycin B, a new aminoglycoside antibiotic (author's transl)].

Authors: M Akiyoshi; K Sato; H Nakada; T Tajima
Journal: Jpn J Antibiot Date: 1974-02

3. Susceptibility of 1,500 isolates of Pseudomonas aeruginosa to gentamicin, carbenicillin, colistin, and polymyxin B.

Authors: I B Duncan
Journal: Antimicrob Agents Chemother Date: 1974-01 Impact factor: 5.191

4. Nephrotoxicity of aminoglycosides and gentamicin.

Authors: F G Falco; H M Smith; G M Arcieri
Journal: J Infect Dis Date: 1969 Apr-May Impact factor: 5.226

5. Nephrotoxicity of gentamicin.

Authors: J C Kosek; R I Mazze; M J Cousins
Journal: Lab Invest Date: 1974-01 Impact factor: 5.662

6. Ototoxicity of gentamicin.

Authors: J Wersäll; P G Lundquist; B Björkroth
Journal: J Infect Dis Date: 1969 Apr-May Impact factor: 5.226

7. In vitro antibiotic susceptibility of pseudomonads other than Pseudomonas aeruginosa recovered from cancer patients.

Authors: M R Moody; V M Young; D M Kenton
Journal: Antimicrob Agents Chemother Date: 1972-11 Impact factor: 5.191

8. SCE-129, antipseudomonal cephalosporin: in vitro and in vivo antibacterial activities.

Authors: K Tsuchiya; M Kondo; H Nagatomo
Journal: Antimicrob Agents Chemother Date: 1978-02 Impact factor: 5.191

9. Carbenicillin resistance in Pseudomonas aeruginosa from clinical material.

Authors: J H Darrell; P M Waterworth
Journal: Br Med J Date: 1969-07-19

10. Synergistic effect of combinations of sulfamethoxazole, trimethoprim, and colistin against Pseudomonas maltophilia and Pseudomonas cepacia.

Authors: C E Nord; T Wadström; B Wretlind
Journal: Antimicrob Agents Chemother Date: 1974-10 Impact factor: 5.191

4 in total

4. In vitro antibacterial activity and susceptibility of cefsulodin, an antipseudomonal cephalosporin, to beta-lactamases.

Authors: A King; K Shannon; I Phillips
Journal: Antimicrob Agents Chemother Date: 1980-02 Impact factor: 5.191