T R Blattert1, G Delling, A Weckbach. 1. Unfall- und Wiederherstellungschirurgie der Chirurgischen Universitätsklinik Würzbug, Josef-Schneider-Strasse 2, 97080 Würzburg. blattert@chirurgie.uni-wuerzburg.de
Abstract
OBJECTIVE: Failure of transpedicular bone-grafting in thoracolumbar burst-fractures has been proven. Possible reasons are insufficient disc-removal and difficult decortication of endplates. Methodical improvements are sought to make the procedure succeed in a sheep-model. METHOD: 12 sheep with posterior instrumentation L4/L6 and transpedicular disremoval L4/L5 underwent auto-grafting. Classical surgical technique was modified by bilateral approach and transpedicular endoscopic control. Animals were sacrificed 8 weeks p.op. For evaluation, radiology, histology, histomorphometry, and fluorochrome-analysis were employed. RESULTS: 10 animals could be evaluated. All revealed sufficient disc-removal and decortication with autograft-impaction into the lower vertebra L4. Main restoration took place before week 4 p.op. Fusion rate was 1/10. For 9/10 animals, defects in the disc-space were filled with metaplastic chondral-tissue; autograft was almost entirely resorbed. CONCLUSIONS: Reason for failure of the method seems to be the insufficient primary stability of the posterior instrumentation, since satisfactory disc-removal and decortication alone cannot successfully modify the method.
OBJECTIVE: Failure of transpedicular bone-grafting in thoracolumbar burst-fractures has been proven. Possible reasons are insufficient disc-removal and difficult decortication of endplates. Methodical improvements are sought to make the procedure succeed in a sheep-model. METHOD: 12 sheep with posterior instrumentation L4/L6 and transpedicular disremoval L4/L5 underwent auto-grafting. Classical surgical technique was modified by bilateral approach and transpedicular endoscopic control. Animals were sacrificed 8 weeks p.op. For evaluation, radiology, histology, histomorphometry, and fluorochrome-analysis were employed. RESULTS: 10 animals could be evaluated. All revealed sufficient disc-removal and decortication with autograft-impaction into the lower vertebra L4. Main restoration took place before week 4 p.op. Fusion rate was 1/10. For 9/10 animals, defects in the disc-space were filled with metaplastic chondral-tissue; autograft was almost entirely resorbed. CONCLUSIONS: Reason for failure of the method seems to be the insufficient primary stability of the posterior instrumentation, since satisfactory disc-removal and decortication alone cannot successfully modify the method.
Authors: Uta Lange; Sebastian Edeling; Christian Knop; Leonard Bastian; Michael Oeser; Christian Krettek; Michael Blauth Journal: Eur Spine J Date: 2006-05-13 Impact factor: 3.134