Literature DB >> 12242980

[Long-term outcome of myotomy and semi-fundoplication in achalasia].

T Junginger1, W Kneist, F Sultanov, V F Eckardt.   

Abstract

The basic principle behind the treatment of achalasia consists of alleviating swallowing disorders by reducing resistance in the lower esophageal sphincter without inducing gastroesophageal reflux. Only a few studies are available on long-term results after operative treatment. Fifty-one patients were studied with regard to long-term results after open transabdominal extramucosal myotomy of the distal esophagus along with partial anterior fundoplication (Dor procedure). Clinical data were collected by standardized interviews, and symptoms were assigned a score ranging from 0 to 3 according to severity and frequency. The pre- and postoperative symptoms were comparable in 50 patients. The median duration of follow-up was 88 months (range: 12-160 months). Operative time was a median of 80 min. Two esophageal mucosal tears were recognized intraoperatively and promptly repaired. Postoperative morbidity occurred in two patients (3.9%). Very good or good long-term results after surgical therapy were achieved in 49 patients (96.1%). Forty-seven patients (92.2%) have no or rare dysphagia. The frequency of regurgitation as well as chest pain was also significantly reduced after surgery. Forty-nine patients (96.1%) either maintained or gained weight. Preoperative duration of symptoms, follow-up, age, and gender had no influence on the results (p > 0.05). Two patients (3.9%) mentioned occasional heartburn. Five patients (9.8%) took or still take proton pump inhibitors postoperatively. Severe stage IV symptoms due to peptic stricture and dolichomegaesophagus required reoperation in one patient (2%). The results show that myotomy and the antireflux procedure (semifundoplication) lead to long-term relief of dysphagia without inducing reflux at a low operative risk. Since long-term results are as yet not available for minimally invasive surgery, it remains to be seen if this operative technique will become the primary surgical procedure for this disease.

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Year:  2002        PMID: 12242980     DOI: 10.1007/s00104-002-0474-9

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  2 in total

1.  Anterior partial fundoplication for gastroesophageal reflux disease.

Authors:  W Kneist; A Heintz; T T Trinh; T Junginger
Journal:  Langenbecks Arch Surg       Date:  2003-07-05       Impact factor: 3.445

2.  New endoscopic indicator of esophageal achalasia: "pinstripe pattern".

Authors:  Hitomi Minami; Hajime Isomoto; Satoshi Miuma; Yasutoshi Kobayashi; Naoyuki Yamaguchi; Shigetoshi Urabe; Kayoko Matsushima; Yuko Akazawa; Ken Ohnita; Fuminao Takeshima; Haruhiro Inoue; Kazuhiko Nakao
Journal:  PLoS One       Date:  2015-02-09       Impact factor: 3.240

  2 in total

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