Literature DB >> 12241722

Oesophageal cancer: a common malignancy in young people of Bomet District, Kenya.

Russell E White1, Christian C Abnet, Caesar K Mungatana, Sanford M Dawsey.   

Abstract

Oesophageal cancer is a common cancer with uneven geographical distribution. We reviewed all malignancies diagnosed at Tenwek Hospital (Bomet District, Kenya) between 1989 and 1998. Oesophageal cancer was the most common malignancy; 274 cases accounted for 19% of 1459 malignancies diagnosed, and for a steady rise in total cancer cases during this period. A striking feature of our study was the presence of a subset of very young patients. 26 (11%) patients were aged 30 years or less at diagnosis, and the youngest patient was 14 years old. This area of West Kenya seems to be a high-risk region for oesophageal cancer.

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Year:  2002        PMID： 12241722     DOI： 10.1016/S0140-6736(02)09639-3

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  18 in total

1.  The incidence of oesophageal cancer in Eastern Africa: identification of a new geographic hot spot?

Authors:  Michael L Cheng; Li Zhang; Margaret Borok; Eric Chokunonga; Charles Dzamamala; Anne Korir; Henry R Wabinga; Robert A Hiatt; D Max Parkin; Katherine Van Loon
Journal:  Cancer Epidemiol       Date:  2015-02-03       Impact factor: 2.984

2.  Clinical and epidemiologic variations of esophageal cancer in Tanzania.

Authors:  Jaime V Gabel; Robert M Chamberlain; Twalib Ngoma; Julius Mwaiselage; Kendra K Schmid; Crispin Kahesa; Amr S Soliman
Journal:  World J Gastrointest Oncol       Date:  2016-03-15

Review 3.  Esophageal cancer in young people: a case series of 109 cases and review of the literature.

Authors:  Sonja P Dawsey; Stanley Tonui; Robert K Parker; John W Fitzwater; Sanford M Dawsey; Russell E White; Christian C Abnet
Journal:  PLoS One       Date:  2010-11-22       Impact factor: 3.240

4.  Alcohol and acetaldehyde in African fermented milk mursik--a possible etiologic factor for high incidence of esophageal cancer in western Kenya.

Authors:  Mikko T Nieminen; Lily Novak-Frazer; Rebecca Collins; Sonja P Dawsey; Sanford M Dawsey; Christian C Abnet; Russell E White; Neal D Freedman; Michael Mwachiro; Paul Bowyer; Mikko Salaspuro; Riina Rautemaa
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2012-11-15       Impact factor: 4.254

Review 5.  Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting-specific exposures to known and putative risk factors.

Authors:  V A McCormack; D Menya; M O Munishi; C Dzamalala; N Gasmelseed; M Leon Roux; M Assefa; O Osano; M Watts; A O Mwasamwaja; B T Mmbaga; G Murphy; C C Abnet; S M Dawsey; J Schüz
Journal:  Int J Cancer       Date:  2016-08-24       Impact factor: 7.396

6.  Frequent occurrence of esophageal cancer in young people in western Kenya.

Authors:  R K Parker; S M Dawsey; C C Abnet; R E White
Journal:  Dis Esophagus       Date:  2009-05-15       Impact factor: 3.429

7.  Cancer epidemiology fieldwork in a resource-limited setting: Experience from the western Kenya ESCCAPE esophageal cancer case-control pilot study.

Authors:  Diana Menya; Margaret Oduor; Nicholas Kigen; Stephen K Maina; Fatma Some; Caroline Kibosia; David Chumba; Florence A Murgor; Rafael S Carel; Daniel R S Middleton; Behnoush Abebi-Ardekani; Joachim Schüz; Valerie A McCormack
Journal:  Cancer Epidemiol       Date:  2018-10-06       Impact factor: 2.984

8.  Cancer of the esophagus: histopathological sub-types in northern Uganda.

Authors:  O N Alema; B Iva
Journal:  Afr Health Sci       Date:  2014-03       Impact factor: 0.927

9.  TP53 mutations, human papilloma virus DNA and inflammation markers in esophageal squamous cell carcinoma from the Rift Valley, a high-incidence area in Kenya.

Authors:  Kirtika Patel; Simeon Mining; Johnston Wakhisi; Tarik Gheit; Massimo Tommasino; Ghislaine Martel-Planche; Pierre Hainaut; Behnoush Abedi-Ardekani
Journal:  BMC Res Notes       Date:  2011-10-31

10.  Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.

Authors:  Jiarui Yu; Wei Wang; Baolin Liu; Jinling Gu; Siyuan Chen; Yishuang Cui; Guogui Sun
Journal:  J Cancer       Date:  2021-05-10       Impact factor: 4.207
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