| Literature DB >> 12241663 |
Wolfgang Fischbach1, Mariele Goebeler-Kolve, Petr Starostik, Axel Greiner, Hans Konrad Müller-Hermelink.
Abstract
Helicobacter pylori eradication is the initial treatment of choice in localised low-grade gastric MALT (mucosa-associated lymphoid-tissue)-type lymphoma. We describe the natural course of seven patients who refused further oncological treatment for persistent lymphoma after successful eradication of H pylori. Despite persistent clonality, neither lymphoma progression nor high-grade transformation arose during a mean observation period of 34 (range 22-44) months. In view of the favourable course of these patients, a watch-and-wait strategy could be a valid approach to management of this disease.Entities:
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Year: 2002 PMID: 12241663 DOI: 10.1016/S0140-6736(02)09711-8
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321