| Literature DB >> 12241111 |
Mario Mascalchi1, Patrizia Nencini, Marco Nistri, Cristina Sarti, Riccardo Santoni.
Abstract
A patient with suprasellar and brain stem involvement in Erdheim Chester disease (ECD) underwent magnetic resonance (MR) imaging and proton MR spectroscopy (1H MRS) of the ventral pons before and 1, 4 and 18 months after external whole-brain (24 Gy) radiotherapy. By revealing a decrease of the N-acetyl-aspartate/choline ratio in the pons, 1H MR spectroscopy anticipated lesions growth on MR imaging. In line with the results in four patients reported in the literature, our observation indicates that external radiation therapy is not effective for intracranial involvement in ECD.Entities:
Mesh:
Year: 2002 PMID: 12241111 DOI: 10.1023/a:1019649201324
Source DB: PubMed Journal: J Neurooncol ISSN: 0167-594X Impact factor: 4.130