Literature DB >> 12241054

On the role of mi-cK and VDAC in mitochondrial function of heart muscle cells.

Frank ter Veld1, Frank Bruggeman, Jeroen Jeneson, Klaas Nicolay.   

Abstract

A two-compartment kinetic model was used to describe reconstituted systems in which mitochondria compete with pyruvate kinase for kinase-generated ADP. The modelling suggests that cytosolic CK deficiency results in a 50% increase in outer mitochondrial membrane permeability.

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Year:  2002        PMID： 12241054     DOI： 10.1023/a:1020373728609

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  6 in total

1.  The quantitation of ADP diffusion gradients across the outer membrane of heart mitochondria in the presence of macromolecules.

Authors:  Frank Norbert Gellerich; Fanny Dorine Laterveer; Stephan Zierz; Klaas Nicolay
Journal:  Biochim Biophys Acta       Date:  2002-04-22

Review 2.  Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.

Authors:  T Wallimann; M Wyss; D Brdiczka; K Nicolay; H M Eppenberger
Journal:  Biochem J       Date:  1992-01-01       Impact factor: 3.857

3.  Cytoarchitectural and metabolic adaptations in muscles with mitochondrial and cytosolic creatine kinase deficiencies.

Authors:  K Steeghs; F Oerlemans; A de Haan; A Heerschap; L Verdoodt; M de Bie; W Ruitenbeek; A Benders; C Jost; J van Deursen; P Tullson; R Terjung; P Jap; W Jacob; D Pette; B Wieringa
Journal:  Mol Cell Biochem       Date:  1998-07       Impact factor: 3.396

4.  Changes in mRNA expression profile underlie phenotypic adaptations in creatine kinase-deficient muscles.

Authors:  A J de Groof; B Smeets; M J Groot Koerkamp; A N Mul; E E Janssen; H F Tabak; B Wieringa
Journal:  FEBS Lett       Date:  2001-09-28       Impact factor: 4.124

5.  Kinetic, thermodynamic, and developmental consequences of deleting creatine kinase isoenzymes from the heart. Reaction kinetics of the creatine kinase isoenzymes in the intact heart.

Authors:  K W Saupe; M Spindler; J C Hopkins; W Shen; J S Ingwall
Journal:  J Biol Chem       Date:  2000-06-30       Impact factor: 5.157

6.  Muscle creatine kinase-deficient mice. II. Cardiac and skeletal muscles exhibit tissue-specific adaptation of the mitochondrial function.

Authors:  V I Veksler; A V Kuznetsov; K Anflous; P Mateo; J van Deursen; B Wieringa; R Ventura-Clapier
Journal:  J Biol Chem       Date:  1995-08-25       Impact factor: 5.157
  6 in total

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