Literature DB >> 12241039

ECA: control in ecosystems.

Hans V Westerhoff1, Wayne M Getz, Frank Bruggeman, Jan-Hendrik S Hofmeyr, Johann M Rohwer, Jacky L Snoep.   

Abstract

Although metabolic control analysis (MCA) cannot be applied directly to microbial ecological systems because of mass conservation and stoichiometric constraints, we demonstrate here that Hierarchical Control Analysis (HCA) can be applied to such systems. We illustrate the approach for a particular ecosystem example of the biological synthesis of acetic acid from glucose, and uncover some surprising aspects to the control of this miniature ecosystem.

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Year:  2002        PMID： 12241039     DOI： 10.1023/a:1020396906319

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  5 in total

1.  Building the cellular puzzle: control in multi-level reaction networks.

Authors:  J H Hofmeyr; H V Westerhoff
Journal:  J Theor Biol       Date:  2001-02       Impact factor: 2.691

2.  Modular control analysis of slipping enzymes.

Authors:  S Schuster; H V Westerhoff
Journal:  Biosystems       Date:  1999-01       Impact factor: 1.973

3.  DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase.

Authors:  Jacky L Snoep; Coen C van der Weijden; Heidi W Andersen; Hans V Westerhoff; Peter Ruhdal Jensen
Journal:  Eur J Biochem       Date:  2002-03

Review 4.  Bioinformatics, cellular flows, and calculation.

Authors:  H V Westerhoff; W M Getz; H W van Verseveld; J H S Hofmeyr; J L Snoep
Journal:  Ernst Schering Res Found Workshop       Date:  2002

Review 5.  The control of flux.

Authors:  H Kacser; J A Burns
Journal:  Biochem Soc Trans       Date:  1995-05       Impact factor: 5.407
  5 in total

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