Literature DB >> 12240255

3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.

S Obika1, M Onoda, K Morita, J Andoh, M Koizumi, T Imanishi.   

Abstract

Novel oligonucleotide analogues, containing a 3'-amino-2',4'-BNA unit, were successfully synthesized, and they showed superior duplex and triplex forming ability as well as BNA itself, along with remarkable enzymatic stability.

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Year:  2001        PMID： 12240255     DOI： 10.1039/b105640a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  1 in total

1.  Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH.

Authors:  Makoto Koizumi; Koji Morita; Makiko Daigo; Shinya Tsutsumi; Koji Abe; Satoshi Obika; Takeshi Imanishi
Journal:  Nucleic Acids Res       Date:  2003-06-15       Impact factor: 16.971
  1 in total

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