Literature DB >> 12240210

Biosynthesis of the vancomycin group of antibiotics: characterisation of a type III polyketide synthase in the pathway to (S)-3,5-dihydroxyphenylglycine.

T L Li1, O W Choroba, H Hong, D H Williams, J B Spencer.   

Abstract

3,5-dihydroxyphenylacetate, a precursor for the non-proteinogenic amino acid 3,5-dihydroxyphenylglycine occurring in glycopeptide antibiotics, is determined to be catalysed by a type III polyketide synthase using malonyl-CoA as a starter unit.

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Year:  2001        PMID： 12240210     DOI： 10.1039/b106638b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Possibility of bacterial recruitment of plant genes associated with the biosynthesis of secondary metabolites.

Authors:  Helge Björn Bode; Rolf Müller
Journal:  Plant Physiol       Date:  2003-07       Impact factor: 8.340

2.  Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine.

Authors:  H Chen; C C Tseng; B K Hubbard; C T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

3.  Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining.

Authors:  Lijiang Song; Francisco Barona-Gomez; Christophe Corre; Longkuan Xiang; Daniel W Udwary; Michael B Austin; Joseph P Noel; Bradley S Moore; Gregory L Challis
Journal:  J Am Chem Soc       Date:  2006-11-22       Impact factor: 15.419

4.  Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum.

Authors:  Amreesh Parvez; Samir Giri; Gorkha Raj Giri; Monika Kumari; Renu Bisht; Priti Saxena
Journal:  Sci Rep       Date:  2018-04-25       Impact factor: 4.379

Review 5.  Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols.

Authors:  Teresa P Martins; Caroline Rouger; Nathaniel R Glasser; Sara Freitas; Nelly B de Fraissinette; Emily P Balskus; Deniz Tasdemir; Pedro N Leão
Journal:  Nat Prod Rep       Date:  2019-10-16       Impact factor: 13.423
  5 in total

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