Literature DB >> 12240127

Novel spermine-based cationic gemini surfactants for gene delivery.

G Ronsin1, C Perrin, P Guédat, A Kremer, P Camilleri, A J Kirby.   

Abstract

Two types of spermine-based gemini surfactants have been synthesised; structure-activity studies have shown one type to be far superior in gene transection than the other.

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Year:  2001        PMID： 12240127     DOI： 10.1039/b105936j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  Transfection by cationic gemini lipids and surfactants.

Authors:  M Damen; A J J Groenen; S F M van Dongen; R J M Nolte; B J Scholte; M C Feiters
Journal:  Medchemcomm       Date:  2018-07-17       Impact factor: 3.597

2.  Varying the unsaturation in N4,N9-dioctadecanoyl spermines: nonviral lipopolyamine vectors for more efficient plasmid DNA formulation.

Authors:  Osama A A Ahmed; Charareh Pourzand; Ian S Blagbrough
Journal:  Pharm Res       Date:  2006-12-31       Impact factor: 4.200

3.  N4,N9-dioleoyl spermine is a novel nonviral lipopolyamine vector for plasmid DNA formulation.

Authors:  Osama A A Ahmed; Noppadon Adjimatera; Charareh Pourzand; Ian S Blagbrough
Journal:  Pharm Res       Date:  2005-06-08       Impact factor: 4.200

4.  Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery.

Authors:  Hassan M Ghonaim; Shi Li; Ian S Blagbrough
Journal:  Pharm Res       Date:  2008-09-10       Impact factor: 4.200

5.  N1,N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation.

Authors:  Hassan M Ghonaim; Shi Li; Ian S Blagbrough
Journal:  Pharm Res       Date:  2009-10-30       Impact factor: 4.200

6.  Design and synthesis of N4,N9-disubstituted spermines for non-viral siRNA delivery--structure-activity relationship studies of siFection efficiency versus toxicity.

Authors:  Moustafa K Soltan; Hassan M Ghonaim; Mohamed El Sadek; M Abou Kull; Lubna Abd El-aziz; Ian S Blagbrough
Journal:  Pharm Res       Date:  2008-10-09       Impact factor: 4.200

7.  Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA.

Authors:  Debra McLaggan; Noppadon Adjimatera; Kristina Sepcić; Marcel Jaspars; David J MacEwan; Ian S Blagbrough; Roderick H Scott
Journal:  BMC Biotechnol       Date:  2006-01-16       Impact factor: 2.563

8.  DNA compaction induced by a cationic polymer or surfactant impact gene expression and DNA degradation.

Authors:  Marie-Louise Ainalem; Andrew Bartles; Joscha Muck; Rita S Dias; Anna M Carnerup; Daniele Zink; Tommy Nylander
Journal:  PLoS One       Date:  2014-03-26       Impact factor: 3.240

9.  Novel cholesterol-based cationic lipids as transfecting agents of DNA for efficient gene delivery.

Authors:  Jia Ju; Meng-Lei Huan; Ning Wan; Hai Qiu; Si-Yuan Zhou; Bang-Le Zhang
Journal:  Int J Mol Sci       Date:  2015-03-11       Impact factor: 5.923
  9 in total

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