Literature DB >> 12240078

A by-product using TIPS protection--a warning.

D J Barden, I Fleming.   

Abstract

The TIPS derivatives of alcohols are contaminated with more or less of the diisopropyl(n-propyl)silyl derivative, which can be a major product when a bad batch of reagent is used, a large excess of reagent is used, and/or the reaction is not taken to completion.

Entities:  

Year:  2001        PMID： 12240078

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  1 in total

1.  Synthesis of the ABC ring system of Azaspiracid. 2. A systematic study into the effect of C(16) and C(17) substitution on bis-spirocyclization.

Authors:  Rich G Carter; David E Graves; Melissa A Gronemeyer; Gregory S Tschumper
Journal:  Org Lett       Date:  2002-06-27       Impact factor: 6.005
  1 in total

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