Literature DB >> 12240056

Stereospecific oxidation by compound I of cytochrome P450 does not proceed in a concerted synchronous manner.

S P de Visser1, F Ogliaro, S Shaik.   

Abstract

Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 12240056     DOI： 10.1039/b105571m

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Epoxidation Catalyzed by the Nonheme Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate.

Authors:  Jikun Li; Hsuan-Jen Liao; Yijie Tang; Jhih-Liang Huang; Lide Cha; Te-Sheng Lin; Justin L Lee; Igor V Kurnikov; Maria G Kurnikova; Wei-Chen Chang; Nei-Li Chan; Yisong Guo
Journal:  J Am Chem Soc       Date:  2020-03-16       Impact factor: 15.419

2.  Xylene monooxygenase, a membrane-spanning non-heme diiron enzyme that hydroxylates hydrocarbons via a substrate radical intermediate.

Authors:  Rachel N Austin; Kate Buzzi; Eungbin Kim; Gerben J Zylstra; John T Groves
Journal:  J Biol Inorg Chem       Date:  2003-06-14       Impact factor: 3.358
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.