Literature DB >> 1223891

Effect of aluminum upon conditioned avoidance response acquisition in the absence of neurofibrillary degeneration.

G A King, U De Boni, D R Crapper.   

Abstract

Aluminum induces neurofibrillary degeneration in cats but not rats. Cats develop a progressive encephalopathy in which an early manifestation is impaired learning-memory performance. At brain aluminum concentrations of 5 to 6 times that found in cat, rats demonstrate an initial transient weight loss and acquisition deficit immediately following intracranial injection. However, rats do not develop a progressive encephalopathy or a chronic learning deficit.

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Year:  1975        PMID: 1223891     DOI: 10.1016/0091-3057(75)90008-8

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  5 in total

1.  Studies of aluminum neurobehavioral toxicity in the intact mammal.

Authors:  R A Yokel; D D Allen; J J Meyer
Journal:  Cell Mol Neurobiol       Date:  1994-12       Impact factor: 5.046

2.  Intranuclear aluminum content in Alzheimer's disease, dialysis encephalopathy, and experimental aluminum encephalopathy.

Authors:  D R Crapper; S Quittkat; S S Krishnan; A J Dalton; U De Boni
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

3.  Impairment of motor coordination in mice after ingestion of aluminum chloride.

Authors:  G Sahin; T Taşkin; K Benli; S Duru
Journal:  Biol Trace Elem Res       Date:  1995-10       Impact factor: 3.738

Review 4.  Metabolism and possible health effects of aluminum.

Authors:  P O Ganrot
Journal:  Environ Health Perspect       Date:  1986-03       Impact factor: 9.031

5.  Cognitive deterioration and associated pathology induced by chronic low-level aluminum ingestion in a translational rat model provides an explanation of Alzheimer's disease, tests for susceptibility and avenues for treatment.

Authors:  J R Walton
Journal:  Int J Alzheimers Dis       Date:  2012-07-30
  5 in total

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