Literature DB >> 12237813

Screening of selected plant extracts for in vitro inhibitory activity on human immunodeficiency virus.

L M Bedoya1, S Sanchez Palomino, M J Abad, P Bermejo, J Alcami.   

Abstract

As part of our screening of anti-AIDS agents from natural sources, extracts of 15 medicinal plants widely used in the folk medicines of North America and Europe were evaluated in vitro. Most of the extracts tested were relatively nontoxic to human lymphocytic MT-2 cells, but only the extracts of Hysopp officinalis and Dittrichia viscosa exhibited anti-HIV activity in an in vitro MTT assay. The 50% hydroalcohol extract of Hysopp officinalis and the aqueous extract of Dittrichia viscosa showed inhibitory effects against HIV-1 induced infections in MT-2 cells at concentrations ranging from 50 to 100 microg/mL and 25 to 400 microg/mL, respectively. Both extracts showed no appreciable cytotoxicity at these concentrations. Copyright 2002 John Wiley & Sons, Ltd.

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Year:  2002        PMID： 12237813     DOI： 10.1002/ptr.992

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  7 in total

1.  Celastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication.

Authors:  Vivek Narayan; Kodihalli C Ravindra; Chris Chiaro; Daniele Cary; Bharat B Aggarwal; Andrew J Henderson; K Sandeep Prabhu
Journal:  J Mol Biol       Date:  2011-07-29       Impact factor: 5.469

2.  Cytotoxicity of Medicinal Plant Species Used by Traditional Healers in Treating People Suffering From HIV/AIDS in Uganda.

Authors:  Godwin Upoki Anywar; Esezah Kakudidi; Hannington Oryem-Origa; Andreas Schubert; Christian Jassoy
Journal:  Front Toxicol       Date:  2022-05-02

3.  Pilot study investigating the ability of an herbal composite to alleviate clinical signs of respiratory dysfunction in horses with recurrent airway obstruction.

Authors:  Wendy Pearson; Armen Charch; Dyanne Brewer; Andrew F Clarke
Journal:  Can J Vet Res       Date:  2007-04       Impact factor: 1.310

4.  Biological activity of Dittrichia viscosa (L.) Greuter extracts against adult Sitophilus granarius (L.) (Coleoptera, Curculionidae) and identification of active compounds.

Authors:  Giuseppe Rotundo; Gianluca Paventi; Antonia Barberio; Antonio De Cristofaro; Ivan Notardonato; Mario V Russo; Giacinto S Germinara
Journal:  Sci Rep       Date:  2019-04-23       Impact factor: 4.379

Review 5.  Potential of selected Lamiaceae plants in anti(retro)viral therapy.

Authors:  Maja Bekut; Snežana Brkić; Nebojša Kladar; Gordana Dragović; Neda Gavarić; Biljana Božin
Journal:  Pharmacol Res       Date:  2017-12-16       Impact factor: 7.658

Review 6.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923

7.  Anti-Viral Activity of Indian Plants.

Authors:  B N Dhawan
Journal:  Proc Natl Acad Sci India Sect B Biol Sci       Date:  2012-01-18
  7 in total

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