Literature DB >> 12237737

Blood substitutes and oxygen therapeutics: an overview and current status.

Jonathan S Jahr1, Susmita B Nesargi, Kenneth Lewis, Calvin Johnson.   

Abstract

This review article discusses the development and implementation of a number of blood substitutes, including hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbons. This review article will introduce the reader to blood substitutes by discussing an overview of an ideal blood substitute, the history of HBOCs and perfluorocarbons, strategies of oxygen carrying, side effects of HBOCs and perfluorocarbons, current clinical trials, and the future of blood substitutes.

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Year:  2002        PMID： 12237737     DOI： 10.1097/00045391-200209000-00012

Source DB:  PubMed          Journal:  Am J Ther        ISSN： 1075-2765            Impact factor:   2.688


  5 in total

1.  Current Challenges in the Development of Acellular Hemoglobin Oxygen Carriers by Protein Engineering.

Authors:  Andres S Benitez Cardenas; Premila P Samuel; John S Olson
Journal:  Shock       Date:  2019-10       Impact factor: 3.454

2.  Inhaled nitric oxide enables artificial blood transfusion without hypertension.

Authors:  Binglan Yu; Michael J Raher; Gian Paolo Volpato; Kenneth D Bloch; Fumito Ichinose; Warren M Zapol
Journal:  Circulation       Date:  2008-04-07       Impact factor: 29.690

3.  Functional characterization of the purified holo form of hemoglobin I from Lucina pectinata overexpressed in Escherichia coli.

Authors:  Evys Collazo; Ruth Pietri; Walleska De Jesús; Cacimar Ramos; Ana Del Toro; Ruth Gretchen León; Carmen L Cadilla; Juan López-Garriga
Journal:  Protein J       Date:  2004-05       Impact factor: 2.371

4.  Evaluating the Effects of Subnormothermic Perfusion with AP39 in a Novel Blood-Free Model of Ex Vivo Kidney Preservation and Reperfusion.

Authors:  Smriti Juriasingani; Ashley Jackson; Max Yulin Zhang; Aushanth Ruthirakanthan; George J Dugbartey; Emrullah Sogutdelen; Max Levine; Moaath Mandurah; Matthew Whiteman; Patrick Luke; Alp Sener
Journal:  Int J Mol Sci       Date:  2021-07-02       Impact factor: 5.923

Review 5.  Hemoglobin-based oxygen carriers.

Authors:  A Gerson Greenburg; Hae Won Kim
Journal:  Crit Care       Date:  2004-06-14       Impact factor: 9.097
  5 in total

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