Literature DB >> 12237547

Removal of fine powders from film surface. I. Effect of electrostatic force on the removal efficiency.

Satoru Watano1, Tomohiro Hamashita, Teruo Suzuki.   

Abstract

A novel fine particle removal system composed of a corona-discharge neutralizer, a pulse-jet air unit and an image processing system has been developed. First of all, adhesion force between particle and film was directly measured and effect of electrostatic force on the adhesion force was calculated experimentally and theoretically. The electrostatic force was found to be significant, leading to the suggestion that the countermeasure for the electrostatic force was required to effectively remove fine particles. This system was then applied to the removal of fine particles from surface of a gelatin film used for conventional capsule material. The number of particles removed by the system was calculated by an image processing system and number base removal efficiency was computed with and without the elimination of electrostatic charge by the neutralizer. It was found that the difference between the removal efficiency of particles with elimination of electrostatic charge and that of without the elimination showed linear relationship with the electrostatic adhesion force. The data confirmed the necessity of electrostatic charge elimination for the effective removal of fine particles.

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Year:  2002        PMID: 12237547     DOI: 10.1248/cpb.50.1258

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Effect of geometric structure of flow promoting agents on the flow properties of pharmaceutical powder mixture.

Authors:  Kotoe Machida Ohta; Musayoshi Fuji; Masatoshi Chikazawa
Journal:  Pharm Res       Date:  2003-05       Impact factor: 4.200

  1 in total

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