Literature DB >> 12237153

Fuzzy pharmacology: theory and applications.

Beth A Sproule1, Claudio A Naranjo, I Burhan Türksen.   

Abstract

Fuzzy pharmacology is a term coined to represent the application of fuzzy logic and fuzzy set theory to pharmacological problems. Fuzzy logic is the science of reasoning, thinking and inference that recognizes and uses the real world phenomenon that everything is a matter of degree. It is an extension of binary logic that is able to deal with complex systems because it does not require crisp definitions and distinctions for the system components. In pharmacology, fuzzy modeling has been used for the mechanical control of drug delivery in surgical settings, and work has begun evaluating its use in other pharmacokinetic and pharmacodynamic applications. Fuzzy pharmacology is an emerging field that, based on these initial explorations, warrants further investigation.

Mesh:

Year:  2002        PMID: 12237153     DOI: 10.1016/s0165-6147(02)02055-2

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


  5 in total

1.  Spline functions in convolutional modeling of verapamil bioavailability and bioequivalence. I: conceptual and numerical issues.

Authors:  J Popović
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2006 Apr-Jun       Impact factor: 2.441

2.  Physiologically based pharmacokinetic modeling of drug disposition in rat and human: a fuzzy arithmetic approach.

Authors:  Kok-Yong Seng; Ivan Nestorov; Paolo Vicini
Journal:  Pharm Res       Date:  2008-03-25       Impact factor: 4.200

3.  Adaptive fuzzy modeling of the hypnotic process in anesthesia.

Authors:  A Marrero; J A Méndez; J A Reboso; I Martín; J L Calvo
Journal:  J Clin Monit Comput       Date:  2016-04-12       Impact factor: 2.502

4.  Computational systems biology in cancer: modeling methods and applications.

Authors:  Wayne Materi; David S Wishart
Journal:  Gene Regul Syst Bio       Date:  2007-09-17

5.  Genetic fuzzy system predicting contractile reactivity patterns of small arteries.

Authors:  J Tang; M Sheykhzade; B F Clausen; H C M Boonen
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2014-04-02
  5 in total

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