OBJECTIVES: To determine the effect of chlorhexidine varnish on the prevention of caries in permanent first molars. METHODS:Two groups of 6-7-year-old school children were followed up in a clinical trial, a group of 86 children whose teeth were treated with achlorhexidine-thymol varnish (Cervitec) and a control group of 95 children. The varnish was reapplied every 3 months and the caries increments were compared at 24 months. RESULTS: The DFS (decayed and filled surfaces in permanent first molars) increment in the control group (mean = 1.85; SD = 2.27) was higher than in the test group (mean = 0.95; SD = 1.38), resulting in a 48.6% caries reduction. This difference was statistically significant (P = 0.032). CONCLUSIONS:Chlorhexidine-thymol varnish is effective in preventing caries in permanent first molars.
RCT Entities:
OBJECTIVES: To determine the effect of chlorhexidine varnish on the prevention of caries in permanent first molars. METHODS: Two groups of 6-7-year-old school children were followed up in a clinical trial, a group of 86 children whose teeth were treated with a chlorhexidine-thymol varnish (Cervitec) and a control group of 95 children. The varnish was reapplied every 3 months and the caries increments were compared at 24 months. RESULTS: The DFS (decayed and filled surfaces in permanent first molars) increment in the control group (mean = 1.85; SD = 2.27) was higher than in the test group (mean = 0.95; SD = 1.38), resulting in a 48.6% caries reduction. This difference was statistically significant (P = 0.032). CONCLUSIONS:Chlorhexidine-thymol varnish is effective in preventing caries in permanent first molars.
Authors: J L Riley; Joshua S Richman; D Brad Rindal; Jeffrey L Fellows; Vibeke Qvist; Gregg H Gilbert; Valeria V Gordan Journal: Oral Health Prev Dent Date: 2010 Impact factor: 1.256
Authors: Sami A Almohefer; John A Levon; Richard L Gregory; George J Eckert; Frank Lippert Journal: J Appl Oral Sci Date: 2018-06-11 Impact factor: 2.698