Literature DB >> 12234572

The genus Hypericum--a valuable resource of anti-Staphylococcal leads.

Simon Gibbons1, Birgit Ohlendorf, Inga Johnsen.   

Abstract

In the present study, extracts of 34 species and varieties of the genus Hypericum were screened for activity against a clinical isolate of methicillin-resistant Staphylococcus aureus, which in addition possessed a multidrug efflux mechanism conferring a high level of resistance to therapeutically useful antibiotics. Thirty-three of the 34 chloroform extracts showed significant activity in a disk diffusion assay, and five extracts had minimum inhibitory concentrations of 64 microg/ml, indicating that this genus has great potential to yield compounds with potent activity against multidrug-resistant bacteria.

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Year:  2002        PMID： 12234572     DOI： 10.1016/s0367-326x(02)00082-5

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  10 in total

Review 1.  Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria.

Authors:  Laura J V Piddock
Journal:  Clin Microbiol Rev       Date:  2006-04       Impact factor: 26.132

2.  Alkyl gallates, intensifiers of beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus.

Authors:  Hirofumi Shibata; Kyoko Kondo; Ryo Katsuyama; Kazuyoshi Kawazoe; Yoichi Sato; Kotaro Murakami; Yoshihisa Takaishi; Naokatu Arakaki; Tomihiko Higuti
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

3.  Bulgarian Medicinal Extracts as Natural Inhibitors with Antiviral and Antibacterial Activity.

Authors:  Ivanka Nikolova; Tsvetelina Paunova-Krasteva; Zdravka Petrova; Petar Grozdanov; Nadya Nikolova; Georgi Tsonev; Alexandros Triantafyllidis; Stoyan Andreev; Madlena Trepechova; Viktoria Milkova; Neli Vilhelmova-Ilieva
Journal:  Plants (Basel)       Date:  2022-06-23

4.  Microwave Assisted Synthesis of 1-[5-(Substituted Aryl)-1H-Pyrazol-3-yl]-3,5-Diphenyl-1H-1,2,4-Triazole as Antinociceptive and Antimicrobial Agents.

Authors:  Shantaram Gajanan Khanage; Popat Baban Mohite; Ramdas Bhanudas Pandhare; S Appala Raju
Journal:  Adv Pharm Bull       Date:  2013-12-24

5.  An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis.

Authors:  Khadijo Osman; Dimitrios Evangelopoulos; Chandrakala Basavannacharya; Antima Gupta; Timothy D McHugh; Sanjib Bhakta; Simon Gibbons
Journal:  Int J Antimicrob Agents       Date:  2011-11-10       Impact factor: 5.283

6.  Ellagic acid derivatives from Rubus ulmifolius inhibit Staphylococcus aureus biofilm formation and improve response to antibiotics.

Authors:  Cassandra L Quave; Miriam Estévez-Carmona; Cesar M Compadre; Gerren Hobby; Howard Hendrickson; Karen E Beenken; Mark S Smeltzer
Journal:  PLoS One       Date:  2012-01-05       Impact factor: 3.240

7.  A novel medium size lactam ring analoges as antibacterial agents: Synthesis, biological evaluation and molecular docking studies.

Authors:  Putcha A N V Harita; Putcha Seshi Kumar; Shiva Krishna Reddy Guduru; Parameshwar Ravula; J N Narendra Sharath Chandra
Journal:  EXCLI J       Date:  2017-08-14       Impact factor: 4.068

8.  The Chemical and Antibacterial Evaluation of St. John's Wort Oil Macerates Used in Kosovar Traditional Medicine.

Authors:  James T Lyles; Austin Kim; Kate Nelson; Angelle L Bullard-Roberts; Avni Hajdari; Behxhet Mustafa; Cassandra L Quave
Journal:  Front Microbiol       Date:  2017-09-08       Impact factor: 5.640

9.  Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes.

Authors:  Afef Béjaoui; Issam Ben Salem; Nesrine Rokbeni; Yassine M'rabet; Mohamed Boussaid; Abdennacer Boulila
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

10.  Dermatological remedies in the traditional pharmacopoeia of Vulture-Alto Bradano, inland southern Italy.

Authors:  Cassandra L Quave; Andrea Pieroni; Bradley C Bennett
Journal:  J Ethnobiol Ethnomed       Date:  2008-02-06       Impact factor: 2.733
  10 in total

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