Literature DB >> 12230248

Synthesis and anticonvulsant properties of new 1-phenyl and 1-phenylamino-3-phenylpyrrolidine-2,5-dione derivatives.

Jolanta Obniska1, Alfred Zeic, Agnieszka Zagórska.   

Abstract

A series of N-aryl and N-aminoaryl 3-phenyl pyrrolidine-2,5-diones were synthesized and tested for anticonvulsant activity in the maximum electroshock seizure (MES) and pentetrazol seizure threshold (sc Met) tests. Structures of the novel compounds were confirmed by elemental and spectral analyses.

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Year:  2002        PMID： 12230248

Source DB:  PubMed          Journal:  Acta Pol Pharm        ISSN： 0001-6837            Impact factor:   0.330


  5 in total

1.  Ethyl 3-hydr-oxy-13-methyl-4'-phenyl-2'-(3,4,5-trimethoxy-phen-yl)-6,7,8,9,11,12,13,14,15,16-deca-hydro-spiro-[cyclo-penta-[a]phenanthrene-16,3'-pyrrolidine]-5'-carboxyl-ate.

Authors:  E Theboral Sugi Kamala; R Murugan; S Nirmala; L Sudha; S Sriman Narayanan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-10-31

2.  Methyl 3-(4-fluoro-phen-yl)-1-methyl-1,2,3,3a,4,9b-hexa-hydro-chromeno[4,3-b]pyrrole-3a-carboxyl-ate.

Authors:  G Chitra Devi; Sundari Bhaskaran; G Usha; G Murugan; M Bakthadoss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-01-12

3.  (3aR*,8bR*)-3a,8b-Dihy-droxy-1-(4-methyl-phen-yl)-2-methyl-sulfanyl-3-nitro-1,8b-di-hydro-indeno-[1,2-b]pyrrol-4(3aH)-one.

Authors:  R A Nagalakshmi; J Suresh; R Ranjith Kumar; V Jeyachandran; P L Nilantha Lakshman
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-02-12

4.  Methyl 4'-(3-bromo-phen-yl)-3'-(2,5-di-methyl-benz-yl)-1'-methyl-2-oxo-spiro-[indo-line-3,2'-pyrrolidine]-3'-carboxyl-ate.

Authors:  S Karthikeyan; K Sethusankar; Anthonisamy Devaraj; Manickam Bakthadoss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-02-15

5.  1'-Allyl-1-(3,4-di-methyl-benzo-yl)-2-(4-methyl-1,3-thia-zol-5-yl)-1,2,5,6,7,7a-hexa-hydro-spiro-[pyrrolizine-3,3'-indolin]-2'-one.

Authors:  V Karthikeyan; V Ramkumar; R Joel Karunakaran
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-04-12
  5 in total

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