Literature DB >> 12230114

Pharmacological evaluation of Shokyo and Kankyo (1).

Kazunori Hashimoto1, Yoshio Kase, Pin Murata, Toshitaka Kido, Yoichiro Nakai, Iwao Sakakibara, Masami Higuchi, Hiroshi Sasaki, Minoru Okada.   

Abstract

Zingiberis Rhizoma (Shokyo, [Japanese characters: see text]) showed significant ameliorative effect on the BaCl2-induced delay of gastric emptying in rat. Bioassay-guided fractionation of the aqueous extract of Shokyo resulted in isolation of 6-gingesulfonic acid (1) and shogasulfonic acid A (3). These compounds significantly improved the delay of gastric emptying on both BaCl2-induced and N(G)-nitro-L-arginine (L-NNA)-induced model in rat. Zingiberis Siccatum Rhizoma (Kankyo, [Japanese characters: see text]) had significant efficacy against castor oil-induced diarrhea. In addition, Kankyo showed the activity increasing intestinal blood flow in normal rat.

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Year:  2002        PMID： 12230114     DOI： 10.1248/bpb.25.1183

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  8 in total

1.  Pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe (Part I).

Authors:  Akitoshi Asami; Tsutomu Shimada; Yasuharu Mizuhara; Takayuki Asano; Shuichi Takeda; Takashi Aburada; Ken-Ichi Miyamoto; Masaki Aburada
Journal:  J Nat Med       Date:  2010-03-19       Impact factor: 2.343

2.  Effect of rikkunshito, a chinese herbal medicine, on stasis in patients after pylorus-preserving gastrectomy.

Authors:  Tsuyoshi Takahashi; Shunji Endo; Kiyokazu Nakajima; Yoshihito Souma; Toshirou Nishida
Journal:  World J Surg       Date:  2009-02       Impact factor: 3.352

3.  Prospective, randomized, cross-over pilot study of the effects of Rikkunshito, a Japanese traditional herbal medicine, on anorexia and plasma-acylated ghrelin levels in lung cancer patients undergoing cisplatin-based chemotherapy.

Authors:  Tomoharu Yoshiya; Takahiro Mimae; Masaoki Ito; Shinsuke Sasada; Yasuhiro Tsutani; Kenichi Satoh; Takeshi Masuda; Yoshihiro Miyata; Noboru Hattori; Morihito Okada
Journal:  Invest New Drugs       Date:  2019-08-19       Impact factor: 3.850

4.  Intragastric administration of rikkunshito stimulates upper gastrointestinal motility and gastric emptying in conscious dogs.

Authors:  Mitsuhiro Yanai; Erito Mochiki; Atsushi Ogawa; Hiroki Morita; Yoshitaka Toyomasu; Kyoichi Ogata; Yuichi Tabe; Hiroyuki Ando; Tetsuro Ohno; Takayuki Asao; Tohru Aomori; Yukiyoshi Fujita; Hiroyuki Kuwano
Journal:  J Gastroenterol       Date:  2012-10-10       Impact factor: 7.527

5.  Effect of rikkunshito, a Japanese herbal medicine, on gastrointestinal symptoms and ghrelin levels in gastric cancer patients after gastrectomy.

Authors:  Shuji Takiguchi; Yuichiro Hiura; Tsuyoshi Takahashi; Yukinori Kurokawa; Makoto Yamasaki; Kiyokazu Nakajima; Hiroshi Miyata; Masaki Mori; Hiroshi Hosoda; Kenji Kangawa; Yuichiro Doki
Journal:  Gastric Cancer       Date:  2012-08-16       Impact factor: 7.370

6.  Clinical effectiveness of KSS formula, a traditional folk remedy for alcohol hangover symptoms.

Authors:  Mizuho Takahashi; Wei Li; Kazuo Koike; Kiyomi Sadamoto
Journal:  J Nat Med       Date:  2010-06-18       Impact factor: 2.343

7.  Effect of drying and processing on diterpenes and other chemical constituents of ginger.

Authors:  Yuto Nishidono; Ken Tanaka
Journal:  J Nat Med       Date:  2022-10-09       Impact factor: 3.192

8.  The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT(3) Receptor Pathway in Rats.

Authors:  K Tominaga; T Kido; M Ochi; C Sadakane; A Mase; H Okazaki; H Yamagami; T Tanigawa; K Watanabe; T Watanabe; Y Fujiwara; N Oshitani; T Arakawa
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-13       Impact factor: 2.629
  8 in total

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