| Literature DB >> 12227765 |
Chaomin Li1, Sujata Bardhan, Emily A Pace, Mei-Chih Liang, Thomas D Gilmore, John A Porco.
Abstract
[reaction: see text] The asymmetric synthesis of the natural product (+)-epoxyquinol A (1) and related epoxyquinoid dimers, employing a cascade oxidation/electrocyclization/Diels-Alder dimerization sequence, is reported. In addition, we show that 1 and related molecules inhibit activation of the transcription factor NF-kappaB.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12227765 DOI： 10.1021/ol026513n
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005