Literature DB >> 12227273

[The relationship between retrobulbar blood flow velocity and glaucoma damage. An intraindividual comparison].

P Breil1, F Krummenauer, S Schmitz, N Pfeiffer.   

Abstract

BACKGROUND: Glaucomatous optic nerve damage is thought to be influenced by ocular perfusion. The aim was to investigate if a difference in visual field and Heidelberg retinal tomography (HRT) between two eyes of an individual glaucoma patient is reflected in different blood flow velocities in retrobulbar vessels.
METHODS: Data from 53 patients including 26 normal tension glaucoma patients (NTG) and 27 high tension glaucoma patients (HTG) were evaluated retrospectively. In 38 patients asymmetric glaucomatous damage (AGD) could be demonstrated by both structural (HRT) and functional measures (static or Goldmann perimetry). In 15 patients there was symmetric glaucomatous damage (SGD). To discriminate between AGD and SGD we used a score for HRT and visual field. Color Doppler imaging (CDI) was performed with a Siemens Quantum 2000.
RESULTS: No significant differences were found when comparing group means of intraindividual deviation of CDI in patients with AGD vs. SGD. Overall analysis of CDI values in NTG vs. HTG eyes also showed no significant differences. Nevertheless we measured decreased blood flow velocities for NTG compared to HTG eyes especially in short posterior ciliary arteries, peak systolic and end diastolic velocities.
CONCLUSIONS: A simple correlation between retrobulbar blood flow velocities and glaucomatous damage could not be found. However, color Doppler images can give important additional information in the diagnosis of glaucoma, especially normal tension glaucoma.

Entities:  

Mesh:

Year:  2002        PMID: 12227273     DOI: 10.1007/s00347-001-0601-x

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  3 in total

1.  Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma.

Authors:  Niklas Plange; Marion Kaup; Oliver Arend; Andreas Remky
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-01-13       Impact factor: 3.117

2.  Slow-stimulated multifocal ERG in high- and normal-tension glaucoma.

Authors:  Anja M Palmowski-Wolfe; Reiner J Allgayer; Bernhild Vernaleken; Andy Schötzau; Klaus W Ruprecht
Journal:  Doc Ophthalmol       Date:  2006-06-19       Impact factor: 2.379

3.  Peripapillary Oxygenation and Retinal Vascular Responsiveness to Flicker Light in Primary Open Angle Glaucoma.

Authors:  Cengiz Türksever; Margarita G Todorova
Journal:  Metabolites       Date:  2022-06-27
  3 in total

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