Literature DB >> 12225385

The interplay of dendritic cell subsets in systemic lupus erythematosus.

A Karolina Palucka1, Jacques Banchereau, Patrick Blanco, Virginia Pascual.   

Abstract

Dendritic cells (DC) control immunity and tolerance. Hence, we surmised that systemic lupus erythematosus (SLE), a systemic autoimmune disease with autoreactive T and B cells, might be due to DC alterations. Based on our findings, we are proposing a model of SLE where autoimmune responses are driven by unabated activation of myeloid DC through IFN-alpha produced by plasmacytoid DC. Thus, interplay between DC subsets might represent a key component of SLE pathogenesis.

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Year:  2002        PMID： 12225385     DOI： 10.1046/j.1440-1711.2002.01112.x

Source DB:  PubMed          Journal:  Immunol Cell Biol        ISSN： 0818-9641            Impact factor:   5.126


  23 in total

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3.  Virginia Pascual, MD: a conversation with the editor.

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Review 4.  Accelerated vascular disease in systemic lupus erythematosus: role of macrophage.

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5.  Ikaros is required for plasmacytoid dendritic cell differentiation.

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Review 6.  Plasmacytoid dendritic cells in HIV infection: striking a delicate balance.

Authors:  Patricia Fitzgerald-Bocarsly; Evan S Jacobs
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7.  A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis.

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Review 8.  Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches.

Authors:  Chary López-Pedrera; Maria Ángeles Aguirre; Nuria Barbarroja; Maria José Cuadrado
Journal:  J Biomed Biotechnol       Date:  2010-09-26

9.  Cancer immunotherapy using dendritic/tumour-fusion vaccine induces elevation of serum anti-nuclear antibody with better clinical responses.

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Journal:  Clin Exp Immunol       Date:  2006-04       Impact factor: 4.330

10.  Deficiency of type I IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease.

Authors:  Hemant Agrawal; Noam Jacob; Esther Carreras; Sandra Bajana; Chaim Putterman; Sean Turner; Barbara Neas; Alexis Mathian; Michael N Koss; William Stohl; Susan Kovats; Chaim O Jacob
Journal:  J Immunol       Date:  2009-10-07       Impact factor: 5.422
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